抄録
Neurons are highly polarized cells with structurally and functionally distinct processes called axons and dendrites. This polarization underlies the directional flow of information in the central nervous system, so the establishment and maintenance of neuronal polarization is crucial for correct development and function. Great progress in our understanding of how neurons establish their polarity has been made through the use of cultured hippocampal neurons, while recent technological advances have enabled in vivo analysis of axon specification and elongation. This short review and accompanying poster highlight recent advances in this fascinating field, with an emphasis on the signaling mechanisms underlying axon and dendrite specification in vitro and in vivo.
本文言語 | English |
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ページ(範囲) | 2088-2093 |
ページ数 | 6 |
ジャーナル | Development (Cambridge) |
巻 | 142 |
号 | 12 |
DOI | |
出版ステータス | Published - 15-06-2015 |
外部発表 | はい |
All Science Journal Classification (ASJC) codes
- Molecular Biology
- Developmental Biology