Neuronal polarization

Tetsuya Takano, Chundi Xu, Yasuhiro Funahashi, Takashi Namba, Kozo Kaibuchi

研究成果: Article査読

68 被引用数 (Scopus)

抄録

Neurons are highly polarized cells with structurally and functionally distinct processes called axons and dendrites. This polarization underlies the directional flow of information in the central nervous system, so the establishment and maintenance of neuronal polarization is crucial for correct development and function. Great progress in our understanding of how neurons establish their polarity has been made through the use of cultured hippocampal neurons, while recent technological advances have enabled in vivo analysis of axon specification and elongation. This short review and accompanying poster highlight recent advances in this fascinating field, with an emphasis on the signaling mechanisms underlying axon and dendrite specification in vitro and in vivo.

本文言語English
ページ(範囲)2088-2093
ページ数6
ジャーナルDevelopment (Cambridge)
142
12
DOI
出版ステータスPublished - 15-06-2015
外部発表はい

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Developmental Biology

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