TY - JOUR
T1 - Nitric oxide inhalation is useful in the management of right ventricular failure caused by myocardial infarction
AU - Fujita, Yoshihito
AU - Nishida, Osamu
AU - Sobue, Kazuya
AU - Ito, Hiroaki
AU - Kusama, Nobuyoshi
AU - Inagaki, Masaaki
AU - Katsuya, Hirotada
PY - 2002/1/1
Y1 - 2002/1/1
N2 - Objective: To describe hemodynamic improvement in a patient treated with nitric oxide (NO) inhalation in the management of right ventricular failure caused by myocardial infarction. Design: Case report. Setting: An intensive care unit of a university hospital. Patient: A 66-yr-old man with severe right ventricular failure caused by acute myocardial infarction. Interventions: Nitric oxide inhalation through a ventilator circuit. Measurements and Main Results: The patient complained of chest pain. When myocardial infarction was diagnosed, he underwent percutaneous transluminal coronary angioplasty and percutaneous transluminal coronary recanalization, but they were not effective. We instituted intra-aortic balloon pumping and brought the patient to the intensive care unit (ICU). Even with high-dose inotropic support, his hemodynamics deteriorated gradually. On the patient's seventh day in the ICU, we started NO inhalation at 5-10 ppm in an attempt to relieve his right heart failure. Immediately after NO inhalation was started, his hemodynamics improved significantly, and we could wean the patient from intra-aortic balloon pumping. NO inhalation was continued for 9 days and was successfully discontinued without circulatory deterioration. He was discharged from our hospital uneventfully. Conclusion: Nitric oxide inhalation improved hemodynamics in our patient with right ventricular failure after myocardial infarction. Our report suggests that a clinical trial of NO treatment for severe right ventricular failure caused by myocardial infarction is warranted.
AB - Objective: To describe hemodynamic improvement in a patient treated with nitric oxide (NO) inhalation in the management of right ventricular failure caused by myocardial infarction. Design: Case report. Setting: An intensive care unit of a university hospital. Patient: A 66-yr-old man with severe right ventricular failure caused by acute myocardial infarction. Interventions: Nitric oxide inhalation through a ventilator circuit. Measurements and Main Results: The patient complained of chest pain. When myocardial infarction was diagnosed, he underwent percutaneous transluminal coronary angioplasty and percutaneous transluminal coronary recanalization, but they were not effective. We instituted intra-aortic balloon pumping and brought the patient to the intensive care unit (ICU). Even with high-dose inotropic support, his hemodynamics deteriorated gradually. On the patient's seventh day in the ICU, we started NO inhalation at 5-10 ppm in an attempt to relieve his right heart failure. Immediately after NO inhalation was started, his hemodynamics improved significantly, and we could wean the patient from intra-aortic balloon pumping. NO inhalation was continued for 9 days and was successfully discontinued without circulatory deterioration. He was discharged from our hospital uneventfully. Conclusion: Nitric oxide inhalation improved hemodynamics in our patient with right ventricular failure after myocardial infarction. Our report suggests that a clinical trial of NO treatment for severe right ventricular failure caused by myocardial infarction is warranted.
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U2 - 10.1097/00003246-200206000-00042
DO - 10.1097/00003246-200206000-00042
M3 - Article
C2 - 12072697
AN - SCOPUS:0036277055
SN - 0090-3493
VL - 30
SP - 1379
EP - 1381
JO - Critical Care Medicine
JF - Critical Care Medicine
IS - 6
ER -