Novel 16S rRNA methyltransferase RmtH produced by Klebsiella pneumoniae associated with war-related trauma

Jessica A. O'Hara, Patrick McGann, Erik C. Snesrud, Robert J. Clifford, Paige E. Waterman, Emil P. Lesho, Yohei Doi

研究成果: Article査読

44 被引用数 (Scopus)

抄録

Klebsiella pneumoniae strain MRSN2404 was isolated from the chronic wound of a soldier who had been wounded in Iraq in 2006. The strain displayed very high MICs of all aminoglycosides, including arbekacin. A gene encoding a novel 16S rRNA methyltransferase, now designated RmtH, was identified. RmtH had 64% identity with RmtB1 and RmtB2. rmtH was bracketed by two copies of ISCR2, which may have played a role in its mobilization.

本文言語English
ページ(範囲)2413-2416
ページ数4
ジャーナルAntimicrobial agents and chemotherapy
57
5
DOI
出版ステータスPublished - 05-2013
外部発表はい

All Science Journal Classification (ASJC) codes

  • 薬理学
  • 薬理学(医学)
  • 感染症

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