TY - JOUR
T1 - Novel Intraoperative Navigation Using Ultra‐High‐Resolution CT in Robot‐Assisted Partial Nephrectomy
AU - Takahara, Kiyoshi
AU - Ohno, Yoshiharu
AU - Fukaya, Kosuke
AU - Matsukiyo, Ryo
AU - Nukaya, Takuhisa
AU - Takenaka, Masashi
AU - Zennami, Kenji
AU - Ichino, Manabu
AU - Fukami, Naohiko
AU - Sasaki, Hitomi
AU - Kusaka, Mamoru
AU - Toyama, Hiroshi
AU - Sumitomo, Makoto
AU - Shiroki, Ryoichi
N1 - Publisher Copyright:
© 2022 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2022/4/1
Y1 - 2022/4/1
N2 - To assess the perioperative and short‐term functional outcomes of robot‐assisted partial nephrectomy (RAPN) with intraoperative navigation using an ultra‐high‐resolution computed tomography (UHR‐CT) scanner, we retrospectively analyzed 323 patients who underwent RAPN using an UHR‐CT or area‐detector CT (ADCT). Perioperative outcomes and the postoperative preservation ratio of estimated glomerular filtration rate (eGFR) were compared. After the propensity score matching, we evaluated 99 patients in each group. Although the median warm ischemia time (WIT) was less than 25 min in both groups, it was significantly shorter in the UHR‐CT group than in the ADCT group (15 min vs. 17 min, p = 0.032). Moreover, the estimated blood loss (EBL) was significantly lower in the UHR‐CT group than in the ADCT group (33 mL vs. 50 mL, p = 0.028). However, there were no significant intergroup differences in the postoperative preservation ratio of eGFR at 3 or 6 months of follow‐up (ADCT 91.8% vs. UHR‐CT 93.5%, p = 0.195; and ADCT 91.7% vs. UHR‐CT 94.0%, p = 0.160, respectively). Although no differences in short‐term renal function were observed in intraoperative navigation for RAPN in this propensity score–matched cohort, this study is the first to demonstrate that UHR‐CT resulted in a shorter WIT and lower EBL than ADCT.
AB - To assess the perioperative and short‐term functional outcomes of robot‐assisted partial nephrectomy (RAPN) with intraoperative navigation using an ultra‐high‐resolution computed tomography (UHR‐CT) scanner, we retrospectively analyzed 323 patients who underwent RAPN using an UHR‐CT or area‐detector CT (ADCT). Perioperative outcomes and the postoperative preservation ratio of estimated glomerular filtration rate (eGFR) were compared. After the propensity score matching, we evaluated 99 patients in each group. Although the median warm ischemia time (WIT) was less than 25 min in both groups, it was significantly shorter in the UHR‐CT group than in the ADCT group (15 min vs. 17 min, p = 0.032). Moreover, the estimated blood loss (EBL) was significantly lower in the UHR‐CT group than in the ADCT group (33 mL vs. 50 mL, p = 0.028). However, there were no significant intergroup differences in the postoperative preservation ratio of eGFR at 3 or 6 months of follow‐up (ADCT 91.8% vs. UHR‐CT 93.5%, p = 0.195; and ADCT 91.7% vs. UHR‐CT 94.0%, p = 0.160, respectively). Although no differences in short‐term renal function were observed in intraoperative navigation for RAPN in this propensity score–matched cohort, this study is the first to demonstrate that UHR‐CT resulted in a shorter WIT and lower EBL than ADCT.
KW - estimated blood loss
KW - robot‐assisted partial nephrectomy
KW - ultra‐high‐resolution computed tomography
KW - warm ischemia time
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U2 - 10.3390/cancers14082047
DO - 10.3390/cancers14082047
M3 - Article
AN - SCOPUS:85128557257
SN - 2072-6694
VL - 14
JO - Cancers
JF - Cancers
IS - 8
M1 - 2047
ER -