Occult macular dystrophy

Y. Miyake, M. Horiguchi, N. Tomita, M. Kondo, A. Tanikawa, H. Takahashi, S. Suzuki, H. Terasaki

研究成果: Article査読

118 被引用数 (Scopus)

抄録

PURPOSE: Occult macular dystrophy is a hereditary macular dystrophy without any visible abnormality of the fundus or abnormality indicated by fluorescein angiography even when visual acuity is decreased. Normal full- field electroretinogram in both cone and rod components with abnormal focal macular cone electroretinogram is the key to diagnosing this disorder. The purpose of this study was to identify the function of the macular rods and to provide detailed clinical findings in occult macular dystrophy. METHODS: Thirteen patients from eight families were examined. The fundi of 12 patients were essentially normal (occult macular dystrophy), and the oldest patient in one family disclosed bull's eye maculopathy. In the 12 patients, including the patient with bull's eye maculopathy, the profiles of cone and rod absolute thresholds were performed across the 60-degree horizontal meridian of the posterior pole. RESULTS: All 12 patients showed cone sensitivity loss only in the macular area. Six relatively young patients revealed normal rod sensitivity, whereas six older patients showed borderline rod sensitivity or abnormal rod sensitivity in the macular area. CONCLUSIONS: The pathology of occult dystrophy involves either only the macular cone system or macular cone and rod systems without any visible abnormality. This difference of the pathology suggests a different clinical entity or a different stage of occult macular dystrophy.

本文言語English
ページ(範囲)644-653
ページ数10
ジャーナルAmerican journal of ophthalmology
122
5
DOI
出版ステータスPublished - 1996
外部発表はい

All Science Journal Classification (ASJC) codes

  • 眼科学

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