TY - JOUR
T1 - Octreotide improved the quality of life in a child with malignant bowel obstruction caused by peritoneal dissemination of colon cancer
AU - Watanabe, Hideki
AU - Inoue, Yasuhiro
AU - Uchida, Keiichi
AU - Okugawa, Yoshinaga
AU - Hiro, Junichiro
AU - Ojima, Eiki
AU - Kobayashi, Minako
AU - Miki, Chikao
AU - Kusunoki, Masato
PY - 2007/1
Y1 - 2007/1
N2 - This is a first pediatric case about the efficacy of octreotide for improving symptoms of malignant bowel obstruction. A 12-year-old boy was referred to our hospital for treatment of transverse colon cancer with peritoneal dissemination. A transverse colectomy was undertaken with postoperative adjuvant chemotherapy. Seven months later, severe abdominal symptoms occurred caused by incomplete bowel obstruction owing to tumor progression. The patient's quality of life decreased with a resultant disturbed mental condition. His parents sought to stop chemotherapy and for him to receive palliative care at home. We suggested nasogastric tube placement, but this was rejected. After obtaining informed consent, octreotide was administered intravenously. After 1 week, abdominal symptoms improved and the boy's complaints stopped. He had a good appetite and was able to eat small amounts of food. He was able to spend his final 2 months at home without nausea and in his family surroundings.
AB - This is a first pediatric case about the efficacy of octreotide for improving symptoms of malignant bowel obstruction. A 12-year-old boy was referred to our hospital for treatment of transverse colon cancer with peritoneal dissemination. A transverse colectomy was undertaken with postoperative adjuvant chemotherapy. Seven months later, severe abdominal symptoms occurred caused by incomplete bowel obstruction owing to tumor progression. The patient's quality of life decreased with a resultant disturbed mental condition. His parents sought to stop chemotherapy and for him to receive palliative care at home. We suggested nasogastric tube placement, but this was rejected. After obtaining informed consent, octreotide was administered intravenously. After 1 week, abdominal symptoms improved and the boy's complaints stopped. He had a good appetite and was able to eat small amounts of food. He was able to spend his final 2 months at home without nausea and in his family surroundings.
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U2 - 10.1016/j.jpedsurg.2006.09.025
DO - 10.1016/j.jpedsurg.2006.09.025
M3 - Article
C2 - 17208578
AN - SCOPUS:33845964187
SN - 0022-3468
VL - 42
SP - 259
EP - 260
JO - Journal of Pediatric Surgery
JF - Journal of Pediatric Surgery
IS - 1
ER -