On- and off-responses in photopic electroretinogram in complete and incomplete types of congenital stationary night blindness

Y. Miyake, K. Yagasaki, M. Horiguchi, Y. Kawase

研究成果: Article査読

113 被引用数 (Scopus)

抄録

The on- and off-responses of photopic electroretinogram (ERG) were recorded by rectangular light stimuli in 13 patients with complete type and 9 patients with incomplete type of congenital stationary night blindness. The positive on-response (b-wave) was significantly smaller in both types than in normal subjects (P < 0.001). The rapid off-response was normal in complete type patients, but was significantly smaller in incomplete type patients than in normal subjects (P < 0.001). Since the rapid off-response mainly reflects the decay of the late receptor potential of the cones, incomplete type patients may have a visual disturbance in the cone itself. Normal rapid off-response with abnormal on-response in complete type patients suggests the existence of a photopic visual disturbance in the middle retinal layer. These results strongly suggest that these two types of congenital stationary night blindness have a different pathogenesis in the photopic visual pathway.

本文言語English
ページ(範囲)81-87
ページ数7
ジャーナルJapanese Journal of Ophthalmology
31
1
出版ステータスPublished - 01-01-1987
外部発表はい

All Science Journal Classification (ASJC) codes

  • 眼科学

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