Oncologic and obstetric outcomes of early stage cervical cancer with abdominal radical trachelectomy: Single-institution experience

Satoshi Tamauchi, Hiroaki Kajiyama, Jun Sakata, Ryuichiro Sekiya, Shiro Suzuki, Mika Mizuno, Fumi Utsumi, Kaoru Niimi, Tomomi Kotani, Kiyosumi Shibata, Fumitaka Kikkawa

研究成果: Article査読

11 被引用数 (Scopus)

抄録

Aim: Radical trachelectomy (RT) is a widely used fertility-sparing treatment for patients with early cervical cancer (CCA). RT, however, is an investigational treatment, and its gynecological and obstetric efficacy are being investigated. We retrospectively assessed the efficacy of abdominal RT (ART) as a fertility-sparing surgery. Methods: From 2010 to 2014, patients with stage IA2–IB1 CCA (tumor ≤2 cm) who wished to preserve their fertility underwent ART. The major outcomes were mortality, recurrence, pregnancy complications, and obstetric outcome. Results: Twenty-eight patients received ART. Adjuvant chemotherapy was performed in seven patients because of lymphovascular space invasion. During the median follow-up of 43 months, no recurrences occurred. Twelve women attempted to conceive, and eight of them became pregnant. A total of five children were born, and one baby was full term. Three cases of second trimester, and one case of third trimester preterm births were recorded. Conclusions: Fertility was preserved after ART in a moderate number of patients. The pregnancy and birth rates after ART have been improving, and increasing the full-term birth rate is the next goal. In addition, development of further types of minimally invasive surgery for CCA can be expected.

本文言語English
ページ(範囲)1796-1801
ページ数6
ジャーナルJournal of Obstetrics and Gynaecology Research
42
12
DOI
出版ステータスPublished - 01-12-2016
外部発表はい

All Science Journal Classification (ASJC) codes

  • Obstetrics and Gynaecology

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