TY - JOUR
T1 - Oncolytic activity of naturally attenuated herpes-simplex virus HF10 against an immunocompetent model of oral carcinoma
AU - Takano, Gaku
AU - Esaki, Shinichi
AU - Goshima, Fumi
AU - Enomoto, Atsushi
AU - Hatano, Yoshimi
AU - Ozaki, Haruka
AU - Watanabe, Takahiro
AU - Sato, Yoshitaka
AU - Kawakita, Daisuke
AU - Murakami, Shingo
AU - Murata, Takayuki
AU - Nishiyama, Yukihiro
AU - Iwasaki, Shinichi
AU - Kimura, Hiroshi
N1 - Publisher Copyright:
© 2020
PY - 2021/3/26
Y1 - 2021/3/26
N2 - Immune responses can enhance anti-tumor capacity of viruses; therefore, full investigation of oncolytic virotherapy requires use of non-immunodeficient mice. Since no commercial cell lines are available, we established a murine model for oral carcinoma and evaluated oncolytic activity of HF10, naturally attenuated herpes simplex virus, in vitro and in vivo.
AB - Immune responses can enhance anti-tumor capacity of viruses; therefore, full investigation of oncolytic virotherapy requires use of non-immunodeficient mice. Since no commercial cell lines are available, we established a murine model for oral carcinoma and evaluated oncolytic activity of HF10, naturally attenuated herpes simplex virus, in vitro and in vivo.
UR - https://www.scopus.com/pages/publications/85100380644
UR - https://www.scopus.com/pages/publications/85100380644#tab=citedBy
U2 - 10.1016/j.omto.2020.12.007
DO - 10.1016/j.omto.2020.12.007
M3 - Article
AN - SCOPUS:85100380644
SN - 2372-7705
VL - 20
SP - 220
EP - 227
JO - Molecular Therapy Oncolytics
JF - Molecular Therapy Oncolytics
ER -
