TY - JOUR
T1 - Optimal prosthetic graft design for small diameter vascular grafts
AU - Nishibe, Toshiya
AU - Kondo, Yuka
AU - Muto, Akihito
AU - Dardik, Alan
N1 - Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.
PY - 2007/11
Y1 - 2007/11
N2 - Autogenous vein and arterial grafts, such as great saphenous veins and internal mammary and radial arteries, remain the gold standard conduits for vascular reconstruction. Expanded polytetrafluoroethylene (PTFE) grafts, which exhibit little inflammatory and thrombogenic reactivity, are the most commonly used material of choice for small diameter vascular grafts when autogenous grafts are not available. Several modifications of the basic graft have been attempted to enhance graft healing of expanded PTFE grafts, and little but definite experimental and clinical improvement has been achieved so far. The technique of vascular tissue engineering, in combination with stem cell research, may hold the key for the creation of a practical and successful small diameter prosthetic graft.
AB - Autogenous vein and arterial grafts, such as great saphenous veins and internal mammary and radial arteries, remain the gold standard conduits for vascular reconstruction. Expanded polytetrafluoroethylene (PTFE) grafts, which exhibit little inflammatory and thrombogenic reactivity, are the most commonly used material of choice for small diameter vascular grafts when autogenous grafts are not available. Several modifications of the basic graft have been attempted to enhance graft healing of expanded PTFE grafts, and little but definite experimental and clinical improvement has been achieved so far. The technique of vascular tissue engineering, in combination with stem cell research, may hold the key for the creation of a practical and successful small diameter prosthetic graft.
UR - http://www.scopus.com/inward/record.url?scp=37349115503&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=37349115503&partnerID=8YFLogxK
U2 - 10.2310/6670.2007.00053
DO - 10.2310/6670.2007.00053
M3 - Review article
C2 - 18053420
AN - SCOPUS:37349115503
SN - 1708-5381
VL - 15
SP - 356
EP - 360
JO - Vascular
JF - Vascular
IS - 6
ER -