Organ Preservation

T. Asano, Takashi Kenmochi, K. Isono

研究成果: Article

1 引用 (Scopus)

抄録

Organ procurement is the first step of organ preservation. We have developed "in situ machine wash out technique with CMH solution" for the purpose of rapid cooling and complete elimination of blood. The utility of this technique was confirmed by both experimentally and clinically. Two major techniques have been used for organ preservation. One is a simple cold storage. Using this method, it is easy to transport organs for transplantation. In addition, availability of UW solution is another advantage of this method. The other is a continuous hypothermic perfusion. Despite of complexity and difficulty of organ transportation, this technique has some advantages, such as viability assay and pretreatment of organs before transplantation. In our experimental studies, viability assays of canine liver and pancreas were achieved using a organ perfusion machine. We also succeeded to prolong the survival of canine pancreatic allograft by pretreatment of anti-Ia antibody during perfusion. While, cryopreservation is most suitable for cell preservation like pancreatic islets. Recently, gene technology was applied for organ preservation studies. In the future, this might become a potent tool for studies in this field.

元の言語English
ページ(範囲)958-963
ページ数6
ジャーナルNippon Geka Gakkai zasshi
97
発行部数11
出版物ステータスPublished - 01-01-1996
外部発表Yes

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Organ Preservation
Perfusion
Organ Transplantation
Canidae
Tissue and Organ Procurement
Cryopreservation
Islets of Langerhans
Allografts
Pancreas
Anti-Idiotypic Antibodies
Technology
Liver
Genes

All Science Journal Classification (ASJC) codes

  • Medicine(all)

これを引用

Asano, T., Kenmochi, T., & Isono, K. (1996). Organ Preservation. Nippon Geka Gakkai zasshi, 97(11), 958-963.
Asano, T. ; Kenmochi, Takashi ; Isono, K. / Organ Preservation. :: Nippon Geka Gakkai zasshi. 1996 ; 巻 97, 番号 11. pp. 958-963.
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Asano, T, Kenmochi, T & Isono, K 1996, 'Organ Preservation', Nippon Geka Gakkai zasshi, 巻. 97, 番号 11, pp. 958-963.

Organ Preservation. / Asano, T.; Kenmochi, Takashi; Isono, K.

:: Nippon Geka Gakkai zasshi, 巻 97, 番号 11, 01.01.1996, p. 958-963.

研究成果: Article

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Asano T, Kenmochi T, Isono K. Organ Preservation. Nippon Geka Gakkai zasshi. 1996 1 1;97(11):958-963.