Oxygen-enhanced MR imaging: Correlation with postsurgical lung function in patients with lung cancer

Yoshiharu Ohno, Hiroto Hatabu, Takanori Higashino, Munenobu Nogami, Daisuke Takenaka, Hirokazu Watanabe, Marc Van Cauteren, Masahiro Yoshimura, Miyako Satouchi, Yoshihiro Nishimura, Kazuro Sugimura

研究成果: ジャーナルへの寄稿学術論文査読

68 被引用数 (Scopus)

抄録

PURPOSE: To prospectively determine if lung function as assessed with oxygen-enhanced magnetic resonance (MR) imaging correlates with postsurgical lung function in patients with lung cancer, as compared with quantitative and qualitative findings of computed tomography (CT) and scintigraphy. MATERIALS AND METHODS: Study received institutional review board approval, and informed patient consent was obtained. Thirty consecutive patients (16 men and 14 women, aged 44-81 years; mean age, 65 years) considered candidates for lung resection underwent oxygen-enhanced MR imaging, CT, perfusion scintigraphy, and measurement of forced expiratory volume in 1 second (FEV1). A respiratory-synchronized inversion-recovery half-Fourier single-shot turbo spin-echo MR sequence was used for data acquisition. Correlation of postsurgical lung function (postsurgical FEV1) as determined with oxygen-enhanced MR imaging (FEV1MR), quantitative assessment with CT (FEV 1Quant), qualitative assessment with CT (FEV1Qual), and perfusion scintigraphy (FEV1PS) was conducted with actual postsurgical FEV1, and the limits of agreement of each were determined with Bland-Altman analysis. RESULTS: Correlation between postsurgical FEV1MR and actual postsurgical FEV1 values was excellent (r2 = 0.81, P < .001); it was better than that of FEV 1Qual (r2 = 0.76) and FEV1PS (r2 = 0.77) and similar to that of FEV1Quant (r2 = 0.81) values. The limits of agreement of FEV1MR were between -9.9% and 10.9%. CONCLUSION: Oxygen-enhanced MR imaging can be used to predict posturgical lung function in patients with lung cancer, similar to quantitative CT.

本文言語英語
ページ(範囲)704-711
ページ数8
ジャーナルRadiology
236
2
DOI
出版ステータス出版済み - 08-2005
外部発表はい

All Science Journal Classification (ASJC) codes

  • 放射線学、核医学およびイメージング

フィンガープリント

「Oxygen-enhanced MR imaging: Correlation with postsurgical lung function in patients with lung cancer」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル