TY - JOUR
T1 - Pain relief of oral ulcer by dibucaine-film
AU - Yamamura, Keiko
AU - Yotsuyanagi, Toshihisa
AU - Okamoto, Tomomitsu
AU - Nabeshima, Toshitaka
N1 - Copyright:
Copyright 2007 Elsevier B.V., All rights reserved.
PY - 1999/12/1
Y1 - 1999/12/1
N2 - A water-soluble three-layered oral mucosa-adhesive film made from hydroxypropyl cellulose containing dibucaine (0.25 mg of drug/cm2) was designed for alleviation of severe pain due to oral ulcers, caused by chemotherapy and/or radiotherapy. We report two patients with constant severe pain ulcers treated with the dibucaine film. Patients were asked to record the time that pain was relieved while chewing following first application of the film. Pain relief lasted for 2-5 h after application of the dibucaine film.
AB - A water-soluble three-layered oral mucosa-adhesive film made from hydroxypropyl cellulose containing dibucaine (0.25 mg of drug/cm2) was designed for alleviation of severe pain due to oral ulcers, caused by chemotherapy and/or radiotherapy. We report two patients with constant severe pain ulcers treated with the dibucaine film. Patients were asked to record the time that pain was relieved while chewing following first application of the film. Pain relief lasted for 2-5 h after application of the dibucaine film.
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U2 - 10.1016/S0304-3959(99)00164-5
DO - 10.1016/S0304-3959(99)00164-5
M3 - Article
C2 - 10568871
AN - SCOPUS:0032745086
VL - 83
SP - 625
EP - 626
JO - Pain
JF - Pain
SN - 0304-3959
IS - 3
ER -