抄録
As a proof of concept that removal of blood amyloid-β (Aβ) can reduce Aβ deposition in the brains of patients with Alzheimer's disease, cortices of patients who had undergone hemodialysis (HD), which removes Aβ from the blood, were histochemically analyzed; postmortem brain sections were stained with anti-Aβ antibodies. Brains from patients who had undergone HD had significantly fewer senile plaques than those of patient who had not undergone HD.∗This significant difference was also confirmed by silver staining.∗Our findings suggest that removal of blood Aβ by hemodialysis results in lower accumulation of Aβ in the brain.
本文言語 | 英語 |
---|---|
ページ(範囲) | 997-1002 |
ページ数 | 6 |
ジャーナル | Journal of Alzheimer's Disease |
巻 | 51 |
号 | 4 |
DOI | |
出版ステータス | 出版済み - 12-04-2016 |
All Science Journal Classification (ASJC) codes
- 神経科学一般
- 臨床心理学
- 老年医学
- 精神医学および精神衛生