Peripancreatic vascular involvements of autoimmune pancreatitis

Takuya Ishikawa, Akihiro Itoh, Hiroki Kawashima, Eizaburo Ohno, Yuya Itoh, Yosuke Nakamura, Takeshi Hiramatsu, Ryoji Miyahara, Naoki Ohmiya, Jyunichi Haruta, Hidemi Goto, Yoshiki Hirooka

研究成果: Article

9 引用 (Scopus)

抄録

Background and Aim: Although peripancreatic vascular lesions are occasionally encountered in autoimmune pancreatitis (AIP), there are few reports focusing on these involvements. We aimed to investigate the peripancreatic vascular involvements associated with AIP. Methods: We retrospectively analyzed 54 AIP patients who met the International Consensus Diagnostic Criteria for AIP between July 2003 and October 2010. All of the 54 patients were subjected to multiphasic multidetector computed tomography, and the prevalence, location and prognosis of peripancreatic vascular involvements were investigated. Results: Of the 54 AIP patients, 24 (44.4%) exhibited involvements in the form of peripancreatic vascular lesions (stenoses of the splenic vein in 22 and of the superior mesenteric-portal vein in 13, development of perigastric collateral circulation in 18, gastric varices with a red color sign in one and thrombosis inside the portal vein in one). Diffuse-type AIP was associated with a significantly higher prevalence of vascular involvements compared with focal-type AIP (P=0.033). A total of 14 out of 16 patients who underwent corticosteroid treatment showed improvement in vascular lesions. One case followed up without corticosteroid treatment and presenting an obstruction of the splenic vein exhibited involvements in the form of an infarction and hemorrhagic cysts of the spleen and ultimately underwent distal pancreatectomy and splenectomy. Conclusions: Autoimmune pancreatitis patients show a high prevalence of peripancreatic vascular involvements. Thus, patients with vascular involvements are suitable candidates for steroid therapy with evaluation of its potential merits and demerits, even if they are asymptomatic.

元の言語English
ページ(範囲)1790-1795
ページ数6
ジャーナルJournal of Gastroenterology and Hepatology (Australia)
27
発行部数12
DOI
出版物ステータスPublished - 01-12-2012
外部発表Yes

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Pancreatitis
Blood Vessels
Splenic Vein
Portal Vein
Adrenal Cortex Hormones
Mesenteric Veins
Collateral Circulation
Pancreatectomy
Multidetector Computed Tomography
Esophageal and Gastric Varices
Splenectomy
Infarction
Cysts
Pathologic Constriction
Thrombosis
Therapeutics
Spleen
Color
Steroids

All Science Journal Classification (ASJC) codes

  • Hepatology
  • Gastroenterology

これを引用

Ishikawa, T., Itoh, A., Kawashima, H., Ohno, E., Itoh, Y., Nakamura, Y., ... Hirooka, Y. (2012). Peripancreatic vascular involvements of autoimmune pancreatitis. Journal of Gastroenterology and Hepatology (Australia), 27(12), 1790-1795. https://doi.org/10.1111/j.1440-1746.2012.07248.x
Ishikawa, Takuya ; Itoh, Akihiro ; Kawashima, Hiroki ; Ohno, Eizaburo ; Itoh, Yuya ; Nakamura, Yosuke ; Hiramatsu, Takeshi ; Miyahara, Ryoji ; Ohmiya, Naoki ; Haruta, Jyunichi ; Goto, Hidemi ; Hirooka, Yoshiki. / Peripancreatic vascular involvements of autoimmune pancreatitis. :: Journal of Gastroenterology and Hepatology (Australia). 2012 ; 巻 27, 番号 12. pp. 1790-1795.
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author = "Takuya Ishikawa and Akihiro Itoh and Hiroki Kawashima and Eizaburo Ohno and Yuya Itoh and Yosuke Nakamura and Takeshi Hiramatsu and Ryoji Miyahara and Naoki Ohmiya and Jyunichi Haruta and Hidemi Goto and Yoshiki Hirooka",
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Ishikawa, T, Itoh, A, Kawashima, H, Ohno, E, Itoh, Y, Nakamura, Y, Hiramatsu, T, Miyahara, R, Ohmiya, N, Haruta, J, Goto, H & Hirooka, Y 2012, 'Peripancreatic vascular involvements of autoimmune pancreatitis', Journal of Gastroenterology and Hepatology (Australia), 巻. 27, 番号 12, pp. 1790-1795. https://doi.org/10.1111/j.1440-1746.2012.07248.x

Peripancreatic vascular involvements of autoimmune pancreatitis. / Ishikawa, Takuya; Itoh, Akihiro; Kawashima, Hiroki; Ohno, Eizaburo; Itoh, Yuya; Nakamura, Yosuke; Hiramatsu, Takeshi; Miyahara, Ryoji; Ohmiya, Naoki; Haruta, Jyunichi; Goto, Hidemi; Hirooka, Yoshiki.

:: Journal of Gastroenterology and Hepatology (Australia), 巻 27, 番号 12, 01.12.2012, p. 1790-1795.

研究成果: Article

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T1 - Peripancreatic vascular involvements of autoimmune pancreatitis

AU - Ishikawa, Takuya

AU - Itoh, Akihiro

AU - Kawashima, Hiroki

AU - Ohno, Eizaburo

AU - Itoh, Yuya

AU - Nakamura, Yosuke

AU - Hiramatsu, Takeshi

AU - Miyahara, Ryoji

AU - Ohmiya, Naoki

AU - Haruta, Jyunichi

AU - Goto, Hidemi

AU - Hirooka, Yoshiki

PY - 2012/12/1

Y1 - 2012/12/1

N2 - Background and Aim: Although peripancreatic vascular lesions are occasionally encountered in autoimmune pancreatitis (AIP), there are few reports focusing on these involvements. We aimed to investigate the peripancreatic vascular involvements associated with AIP. Methods: We retrospectively analyzed 54 AIP patients who met the International Consensus Diagnostic Criteria for AIP between July 2003 and October 2010. All of the 54 patients were subjected to multiphasic multidetector computed tomography, and the prevalence, location and prognosis of peripancreatic vascular involvements were investigated. Results: Of the 54 AIP patients, 24 (44.4%) exhibited involvements in the form of peripancreatic vascular lesions (stenoses of the splenic vein in 22 and of the superior mesenteric-portal vein in 13, development of perigastric collateral circulation in 18, gastric varices with a red color sign in one and thrombosis inside the portal vein in one). Diffuse-type AIP was associated with a significantly higher prevalence of vascular involvements compared with focal-type AIP (P=0.033). A total of 14 out of 16 patients who underwent corticosteroid treatment showed improvement in vascular lesions. One case followed up without corticosteroid treatment and presenting an obstruction of the splenic vein exhibited involvements in the form of an infarction and hemorrhagic cysts of the spleen and ultimately underwent distal pancreatectomy and splenectomy. Conclusions: Autoimmune pancreatitis patients show a high prevalence of peripancreatic vascular involvements. Thus, patients with vascular involvements are suitable candidates for steroid therapy with evaluation of its potential merits and demerits, even if they are asymptomatic.

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