pH-stat blood gas management provides better cerebral perfusion during deep hypothermic retrograde cerebral perfusion

Takao Nishizawa; Akihiko Usui; Mitsuya Murase; Yuichi Ueda

doi:10.1016/S1569-9293(02)00057-9

pH-stat blood gas management provides better cerebral perfusion during deep hypothermic retrograde cerebral perfusion

Takao Nishizawa
, Akihiko Usui
, Mitsuya Murase
, Yuichi Ueda

研究成果: ジャーナルへの寄稿 › 総説 › 査読

2 被引用数 (Scopus)

抄録

We performed a retrospective comparative clinical study to evaluate whether pH-stat (n=14) or alpha-stat strategy (n=15) provides better perfusion or oxygen metabolism during hypothermic retrograde cerebral perfusion (RCP). The pH-stat group showed significantly lower superior vena cava (SVC) pressure (21±4 versus 27±6 mmHg, P<0.0001), apparently lower retrograde cerebral vascular resistance index (7.4±2.1 versus 10.1±3.8 dynes/s cm^-5 m^-2, P=0.009) but there were no significant differences in RCP flow index, oxygen supply or oxygen extraction between groups. Further studies are necessary to determine which blood gas management is better for RCP, however, pH-stat strategy should be useful in deep hypothermic RCP.

本文言語	英語
ページ（範囲）	88-92
ページ数	5
ジャーナル	Interactive Cardiovascular and Thoracic Surgery
巻	1
号	2
DOI	https://doi.org/10.1016/S1569-9293(02)00057-9
出版ステータス	出版済み - 12-2002
外部発表	はい

All Science Journal Classification (ASJC) codes

外科
呼吸器内科
循環器および心血管医学

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10.1016/S1569-9293(02)00057-9

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title = "pH-stat blood gas management provides better cerebral perfusion during deep hypothermic retrograde cerebral perfusion",

abstract = "We performed a retrospective comparative clinical study to evaluate whether pH-stat (n=14) or alpha-stat strategy (n=15) provides better perfusion or oxygen metabolism during hypothermic retrograde cerebral perfusion (RCP). The pH-stat group showed significantly lower superior vena cava (SVC) pressure (21±4 versus 27±6 mmHg, P<0.0001), apparently lower retrograde cerebral vascular resistance index (7.4±2.1 versus 10.1±3.8 dynes/s cm-5 m-2, P=0.009) but there were no significant differences in RCP flow index, oxygen supply or oxygen extraction between groups. Further studies are necessary to determine which blood gas management is better for RCP, however, pH-stat strategy should be useful in deep hypothermic RCP.",

author = "Takao Nishizawa and Akihiko Usui and Mitsuya Murase and Yuichi Ueda",

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TY - JOUR

T1 - pH-stat blood gas management provides better cerebral perfusion during deep hypothermic retrograde cerebral perfusion

AU - Nishizawa, Takao

AU - Usui, Akihiko

AU - Murase, Mitsuya

AU - Ueda, Yuichi

PY - 2002/12

Y1 - 2002/12

N2 - We performed a retrospective comparative clinical study to evaluate whether pH-stat (n=14) or alpha-stat strategy (n=15) provides better perfusion or oxygen metabolism during hypothermic retrograde cerebral perfusion (RCP). The pH-stat group showed significantly lower superior vena cava (SVC) pressure (21±4 versus 27±6 mmHg, P<0.0001), apparently lower retrograde cerebral vascular resistance index (7.4±2.1 versus 10.1±3.8 dynes/s cm-5 m-2, P=0.009) but there were no significant differences in RCP flow index, oxygen supply or oxygen extraction between groups. Further studies are necessary to determine which blood gas management is better for RCP, however, pH-stat strategy should be useful in deep hypothermic RCP.

AB - We performed a retrospective comparative clinical study to evaluate whether pH-stat (n=14) or alpha-stat strategy (n=15) provides better perfusion or oxygen metabolism during hypothermic retrograde cerebral perfusion (RCP). The pH-stat group showed significantly lower superior vena cava (SVC) pressure (21±4 versus 27±6 mmHg, P<0.0001), apparently lower retrograde cerebral vascular resistance index (7.4±2.1 versus 10.1±3.8 dynes/s cm-5 m-2, P=0.009) but there were no significant differences in RCP flow index, oxygen supply or oxygen extraction between groups. Further studies are necessary to determine which blood gas management is better for RCP, however, pH-stat strategy should be useful in deep hypothermic RCP.

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UR - https://www.scopus.com/pages/publications/0141704835#tab=citedBy

U2 - 10.1016/S1569-9293(02)00057-9

DO - 10.1016/S1569-9293(02)00057-9

M3 - Review article

AN - SCOPUS:0141704835

SN - 1569-9293

VL - 1

SP - 88

EP - 92

JO - Interactive Cardiovascular and Thoracic Surgery

JF - Interactive Cardiovascular and Thoracic Surgery

IS - 2

ER -

pH-stat blood gas management provides better cerebral perfusion during deep hypothermic retrograde cerebral perfusion

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