Prediction of long-term outcomes in st-elevation myocardial infarction and non-st elevation myocardial infarction with and without creatinine kinase elevation—post-hoc analysis of the j-minuet study

J-MINUET investigators

研究成果: ジャーナルへの寄稿学術論文査読

4 被引用数 (Scopus)

抄録

Background: A Japanese prospective, nation-wide, multicenter registry (J-MINUET) showed that long-term outcomes were worse in non-ST elevation acute myocardial infarction (NSTEMI), diagnosed by increased cardiac troponin levels, compared to STEMI. This was observed in both non-STEMI with elevated creatine kinase (CK) (NSTEMI+CK) and non-STEMI without elevated CK (NSTEMI-CK). However, predictive factors for long-term outcomes in STEMI, NSTEMI+CK, and NSTEMI-CK have not been elucidated. Methods: Using the Cox proportional hazards model, we determined significant independent predictors of long-term outcomes from a total of 111 parameters evaluated in the J-MINUET study in each of our groups, including STEMI, NSTEMI+CK, and NSTEMI-CK. Then, we calculated the risk score using the regression coefficients for the determined independent predictors for the strict prediction of long-term outcomes. Results: Prognostic factors, as well as composite cardiovascular events and all-cause death, were different between STEMI, NSTEMI+CK, and NSTEMI-CK. Risk scores could effectively and powerfully predict both composite cardiovascular events and all-cause death in each group. Conclusions: The prediction of long-term outcomes using cored parameters of baseline demographics and clinical characteristics is feasible and could prove useful in establishing therapeutic strategies in patients with STEMI, NSTEMI+CK, and NSTEMI-CK.

本文言語英語
論文番号2667
ページ(範囲)1-13
ページ数13
ジャーナルJournal of Clinical Medicine
9
8
DOI
出版ステータス出版済み - 08-2020

All Science Journal Classification (ASJC) codes

  • 医学一般

フィンガープリント

「Prediction of long-term outcomes in st-elevation myocardial infarction and non-st elevation myocardial infarction with and without creatinine kinase elevation—post-hoc analysis of the j-minuet study」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル