Preoperative biliary drainage in obstructive jaundice

Y. Kawarada, Takashi Higashiguchi, H. Yokoi, P. Vaidya, R. Mizumoto

研究成果: Article

63 引用 (Scopus)

抄録

Background/Aims: Although the role of preoperative percutaneous transhepatic biliary drainage in obstructive jaundice has been the subject of controversy in many other countries, in Japan, almost all surgeons agree that biliary decompression should be performed prior to the surgical treatment in obstructive jaundice. This study was performed in order to determine the role of preoperative percutaneous transhepatic biliary drainage in obstructive jaundice. Patients and Methods: We evaluated 238 patients with preoperative obstructive jaundice, and also studied its pathophysiology in experimental animal models. Results: Both of these studies demonstrated that this procedure should be performed if the value of total bilirubin is more than 5 mg/dl, the ICG Rmax value of the future remnant liver is less than 0.4 mg/kg/min, and the duration of jaundice is more than 3 weeks. Preoperative biliary drainage improves the liver function, so that major operations can be safely performed without major complications. Conclusions: It therefore seems preferable that patients undergo preoperative biliary decompression to reduce serum total bilirubin to below 5 mg/dl, and to improve hepatic and reticuloendothelial functions and hepatic reserve prior to any major surgical operation.

元の言語English
ページ(範囲)300-307
ページ数8
ジャーナルHepato-Gastroenterology
42
発行部数4
出版物ステータスPublished - 01-01-1995
外部発表Yes

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Obstructive Jaundice
Drainage
Liver
Decompression
Bilirubin
Jaundice
Japan
Animal Models
Serum
Therapeutics

All Science Journal Classification (ASJC) codes

  • Hepatology
  • Gastroenterology

これを引用

Kawarada, Y., Higashiguchi, T., Yokoi, H., Vaidya, P., & Mizumoto, R. (1995). Preoperative biliary drainage in obstructive jaundice. Hepato-Gastroenterology, 42(4), 300-307.
Kawarada, Y. ; Higashiguchi, Takashi ; Yokoi, H. ; Vaidya, P. ; Mizumoto, R. / Preoperative biliary drainage in obstructive jaundice. :: Hepato-Gastroenterology. 1995 ; 巻 42, 番号 4. pp. 300-307.
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Kawarada, Y, Higashiguchi, T, Yokoi, H, Vaidya, P & Mizumoto, R 1995, 'Preoperative biliary drainage in obstructive jaundice', Hepato-Gastroenterology, 巻. 42, 番号 4, pp. 300-307.

Preoperative biliary drainage in obstructive jaundice. / Kawarada, Y.; Higashiguchi, Takashi; Yokoi, H.; Vaidya, P.; Mizumoto, R.

:: Hepato-Gastroenterology, 巻 42, 番号 4, 01.01.1995, p. 300-307.

研究成果: Article

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Kawarada Y, Higashiguchi T, Yokoi H, Vaidya P, Mizumoto R. Preoperative biliary drainage in obstructive jaundice. Hepato-Gastroenterology. 1995 1 1;42(4):300-307.