Prognostic Nutritional Index and Lung Immune Prognostic Index as Prognostic Predictors for Combination Therapies of Immune Checkpoint Inhibitors and Cytotoxic Anticancer Chemotherapy for Patients with Advanced Non-Small Cell Lung Cancer

Satomi Tanaka; Junji Uchino; Takashi Yokoi; Takashi Kijima; Yasuhiro Goto; Yoshifumi Suga; Yuki Katayama; Ryota Nakamura; Kenji Morimoto; Akira Nakao; Makoto Hibino; Nozomi Tani; Takayuki Takeda; Hiroyuki Yamaguchi; Yusuke Tachibana; Chieko Takumi; Noriya Hiraoka; Masafumi Takeshita; Keisuke Onoi; Yusuke Chihara; Ryusuke Taniguchi; Takahiro Yamada; Yohei Matsui; Osamu Hiranuma; Yoshie Morimoto; Masahiro Iwasaku; Shinsaku Tokuda; Yoshiko Kaneko; Tadaaki Yamada; Koichi Takayama

doi:10.3390/diagnostics12020423

Prognostic Nutritional Index and Lung Immune Prognostic Index as Prognostic Predictors for Combination Therapies of Immune Checkpoint Inhibitors and Cytotoxic Anticancer Chemotherapy for Patients with Advanced Non-Small Cell Lung Cancer

Satomi Tanaka
, Junji Uchino
, Takashi Yokoi
, Takashi Kijima
, Yasuhiro Goto
, Yoshifumi Suga
, Yuki Katayama
, Ryota Nakamura
, Kenji Morimoto
, Akira Nakao
, Makoto Hibino
, Nozomi Tani
, Takayuki Takeda
, Hiroyuki Yamaguchi
, Yusuke Tachibana
, Chieko Takumi
, Noriya Hiraoka
, Masafumi Takeshita
, Keisuke Onoi
, Yusuke Chihara

Ryusuke Taniguchi, Takahiro Yamada, Yohei Matsui, Osamu Hiranuma, Yoshie Morimoto, Masahiro Iwasaku, Shinsaku Tokuda, Yoshiko Kaneko, Tadaaki Yamada, Koichi Takayama

医学部・呼吸器内科学

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

36 被引用数 (Scopus)

抄録

Combination therapy with immune checkpoint inhibitors and cytotoxic chemotherapies (chemoimmunotherapy) is associated with significantly better survival outcomes than cytotoxic chemotherapies alone in patients with advanced non-small cell lung cancer (NSCLC). However, there are no prognostic markers for chemoimmunotherapy. The prognostic nutritional index (PNI) and lung immune prognostic index (LIPI) are prognostic biomarkers for immune checkpoint.

本文言語	英語
論文番号	423
ジャーナル	Diagnostics
巻	12
号	2
DOI	https://doi.org/10.3390/diagnostics12020423
出版ステータス	出版済み - 02-2022

UN SDG

この成果は、次の持続可能な開発目標に貢献しています

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All Science Journal Classification (ASJC) codes

内科学
臨床生化学

文献へのアクセス

10.3390/diagnostics12020423

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フィンガープリント

「Prognostic Nutritional Index and Lung Immune Prognostic Index as Prognostic Predictors for Combination Therapies of Immune Checkpoint Inhibitors and Cytotoxic Anticancer Chemotherapy for Patients with Advanced Non-Small Cell Lung Cancer」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル

Tanaka, S., Uchino, J., Yokoi, T., Kijima, T., Goto, Y., Suga, Y., Katayama, Y., Nakamura, R., Morimoto, K., Nakao, A., Hibino, M., Tani, N., Takeda, T., Yamaguchi, H., Tachibana, Y., Takumi, C., Hiraoka, N., Takeshita, M., Onoi, K., ... Takayama, K. (2022). Prognostic Nutritional Index and Lung Immune Prognostic Index as Prognostic Predictors for Combination Therapies of Immune Checkpoint Inhibitors and Cytotoxic Anticancer Chemotherapy for Patients with Advanced Non-Small Cell Lung Cancer. Diagnostics, 12(2), 記事 423. https://doi.org/10.3390/diagnostics12020423

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title = "Prognostic Nutritional Index and Lung Immune Prognostic Index as Prognostic Predictors for Combination Therapies of Immune Checkpoint Inhibitors and Cytotoxic Anticancer Chemotherapy for Patients with Advanced Non-Small Cell Lung Cancer",

abstract = "Combination therapy with immune checkpoint inhibitors and cytotoxic chemotherapies (chemoimmunotherapy) is associated with significantly better survival outcomes than cytotoxic chemotherapies alone in patients with advanced non-small cell lung cancer (NSCLC). However, there are no prognostic markers for chemoimmunotherapy. The prognostic nutritional index (PNI) and lung immune prognostic index (LIPI) are prognostic biomarkers for immune checkpoint.",

keywords = "Advanced non-small cell lung cancer, Chemoimmunotherapy, Lung immune prognostic index, Prognostic nutritional index, Programmed cell death ligand 1",

author = "Satomi Tanaka and Junji Uchino and Takashi Yokoi and Takashi Kijima and Yasuhiro Goto and Yoshifumi Suga and Yuki Katayama and Ryota Nakamura and Kenji Morimoto and Akira Nakao and Makoto Hibino and Nozomi Tani and Takayuki Takeda and Hiroyuki Yamaguchi and Yusuke Tachibana and Chieko Takumi and Noriya Hiraoka and Masafumi Takeshita and Keisuke Onoi and Yusuke Chihara and Ryusuke Taniguchi and Takahiro Yamada and Yohei Matsui and Osamu Hiranuma and Yoshie Morimoto and Masahiro Iwasaku and Shinsaku Tokuda and Yoshiko Kaneko and Tadaaki Yamada and Koichi Takayama",

note = "Publisher Copyright: {\textcopyright} 2022 by the authors. Licensee MDPI, Basel, Switzerland.",

year = "2022",

month = feb,

doi = "10.3390/diagnostics12020423",

language = "English",

volume = "12",

journal = "Diagnostics",

issn = "2075-4418",

publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",

number = "2",

}

Tanaka, S, Uchino, J, Yokoi, T, Kijima, T, Goto, Y, Suga, Y, Katayama, Y, Nakamura, R, Morimoto, K, Nakao, A, Hibino, M, Tani, N, Takeda, T, Yamaguchi, H, Tachibana, Y, Takumi, C, Hiraoka, N, Takeshita, M, Onoi, K, Chihara, Y, Taniguchi, R, Yamada, T, Matsui, Y, Hiranuma, O, Morimoto, Y, Iwasaku, M, Tokuda, S, Kaneko, Y, Yamada, T & Takayama, K 2022, 'Prognostic Nutritional Index and Lung Immune Prognostic Index as Prognostic Predictors for Combination Therapies of Immune Checkpoint Inhibitors and Cytotoxic Anticancer Chemotherapy for Patients with Advanced Non-Small Cell Lung Cancer', Diagnostics, vol. 12, no. 2, 423. https://doi.org/10.3390/diagnostics12020423

Prognostic Nutritional Index and Lung Immune Prognostic Index as Prognostic Predictors for Combination Therapies of Immune Checkpoint Inhibitors and Cytotoxic Anticancer Chemotherapy for Patients with Advanced Non-Small Cell Lung Cancer. / Tanaka, Satomi; Uchino, Junji; Yokoi, Takashi その他.
In: Diagnostics, Vol. 12, No. 2, 423, 02.2022.

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

TY - JOUR

T1 - Prognostic Nutritional Index and Lung Immune Prognostic Index as Prognostic Predictors for Combination Therapies of Immune Checkpoint Inhibitors and Cytotoxic Anticancer Chemotherapy for Patients with Advanced Non-Small Cell Lung Cancer

AU - Tanaka, Satomi

AU - Uchino, Junji

AU - Yokoi, Takashi

AU - Kijima, Takashi

AU - Goto, Yasuhiro

AU - Suga, Yoshifumi

AU - Katayama, Yuki

AU - Nakamura, Ryota

AU - Morimoto, Kenji

AU - Nakao, Akira

AU - Hibino, Makoto

AU - Tani, Nozomi

AU - Takeda, Takayuki

AU - Yamaguchi, Hiroyuki

AU - Tachibana, Yusuke

AU - Takumi, Chieko

AU - Hiraoka, Noriya

AU - Takeshita, Masafumi

AU - Onoi, Keisuke

AU - Chihara, Yusuke

AU - Taniguchi, Ryusuke

AU - Yamada, Takahiro

AU - Matsui, Yohei

AU - Hiranuma, Osamu

AU - Morimoto, Yoshie

AU - Iwasaku, Masahiro

AU - Tokuda, Shinsaku

AU - Kaneko, Yoshiko

AU - Yamada, Tadaaki

AU - Takayama, Koichi

PY - 2022/2

Y1 - 2022/2

N2 - Combination therapy with immune checkpoint inhibitors and cytotoxic chemotherapies (chemoimmunotherapy) is associated with significantly better survival outcomes than cytotoxic chemotherapies alone in patients with advanced non-small cell lung cancer (NSCLC). However, there are no prognostic markers for chemoimmunotherapy. The prognostic nutritional index (PNI) and lung immune prognostic index (LIPI) are prognostic biomarkers for immune checkpoint.

AB - Combination therapy with immune checkpoint inhibitors and cytotoxic chemotherapies (chemoimmunotherapy) is associated with significantly better survival outcomes than cytotoxic chemotherapies alone in patients with advanced non-small cell lung cancer (NSCLC). However, there are no prognostic markers for chemoimmunotherapy. The prognostic nutritional index (PNI) and lung immune prognostic index (LIPI) are prognostic biomarkers for immune checkpoint.

KW - Advanced non-small cell lung cancer

KW - Chemoimmunotherapy

KW - Lung immune prognostic index

KW - Prognostic nutritional index

KW - Programmed cell death ligand 1

UR - https://www.scopus.com/pages/publications/85124263716

UR - https://www.scopus.com/pages/publications/85124263716#tab=citedBy

U2 - 10.3390/diagnostics12020423

DO - 10.3390/diagnostics12020423

M3 - Article

AN - SCOPUS:85124263716

SN - 2075-4418

VL - 12

JO - Diagnostics

JF - Diagnostics

IS - 2

M1 - 423

ER -