Prognostic significance of T-wave amplitude in lead aVR in heart failure patients with narrow QRS complexes

Kentarou Okuda, Eiichi Watanabe, Kan Sano, Tomoharu Arakawa, Mayumi Yamamoto, Yoshihiro Sobue, Tatsushi Uchiyama, Yukio Ozaki

研究成果: Article

10 引用 (Scopus)

抄録

Background: Prolonged duration of the QRS complex is a prognostic marker in patients with heart failure (HF), whereas electrocadiographic markers in HF with narrow QRS complex remain unclear. We evaluated the prognostic value of the T-wave amplitude in lead aVR in HF patients with narrow QRS complexes. Methods: We examined 331 patients who were admitted to our hospital for worsening HF (68 ± 15 years, mean ± standard deviation) from January 2000 to October 2004 who had sinus rhythm and QRS complex <120 ms. The patients were categorized into three groups according to the peak T-wave amplitude from baseline in lead aVR: negative (<-0.1 mV; n = 209, 63%), flat (-0.1-0.1 mV; n = 64, 19%), and positive (>0.1 mV; n = 58, 18%). Results: During a mean follow-up of 33 months, 113 (34%) patients had all-cause death, the primary end point. After adjusting for clinical covariates, flat T wave (hazard ratio [HR] 1.86, 95% confidence interval [CI] 1.42-2.46), and positive T wave (HR 6.76, 95% CI 3.92-11.8) were independent predictors of mortality, when negative T wave was considered a reference. Conclusions: As the peak T-wave amplitude in lead aVR becomes less negative, there was a progressive increase in mortality. The T wave in lead aVR provides prognostic information for risk stratification in HF patients with narrow QRS complexes.

元の言語English
ページ(範囲)250-257
ページ数8
ジャーナルAnnals of Noninvasive Electrocardiology
16
発行部数3
DOI
出版物ステータスPublished - 01-07-2011

Fingerprint

Heart Failure
Confidence Intervals
Mortality
Cause of Death
Lead

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

これを引用

Okuda, Kentarou ; Watanabe, Eiichi ; Sano, Kan ; Arakawa, Tomoharu ; Yamamoto, Mayumi ; Sobue, Yoshihiro ; Uchiyama, Tatsushi ; Ozaki, Yukio. / Prognostic significance of T-wave amplitude in lead aVR in heart failure patients with narrow QRS complexes. :: Annals of Noninvasive Electrocardiology. 2011 ; 巻 16, 番号 3. pp. 250-257.
@article{c1b0d4d9b104478fae9ea3eb1f0db023,
title = "Prognostic significance of T-wave amplitude in lead aVR in heart failure patients with narrow QRS complexes",
abstract = "Background: Prolonged duration of the QRS complex is a prognostic marker in patients with heart failure (HF), whereas electrocadiographic markers in HF with narrow QRS complex remain unclear. We evaluated the prognostic value of the T-wave amplitude in lead aVR in HF patients with narrow QRS complexes. Methods: We examined 331 patients who were admitted to our hospital for worsening HF (68 ± 15 years, mean ± standard deviation) from January 2000 to October 2004 who had sinus rhythm and QRS complex <120 ms. The patients were categorized into three groups according to the peak T-wave amplitude from baseline in lead aVR: negative (<-0.1 mV; n = 209, 63{\%}), flat (-0.1-0.1 mV; n = 64, 19{\%}), and positive (>0.1 mV; n = 58, 18{\%}). Results: During a mean follow-up of 33 months, 113 (34{\%}) patients had all-cause death, the primary end point. After adjusting for clinical covariates, flat T wave (hazard ratio [HR] 1.86, 95{\%} confidence interval [CI] 1.42-2.46), and positive T wave (HR 6.76, 95{\%} CI 3.92-11.8) were independent predictors of mortality, when negative T wave was considered a reference. Conclusions: As the peak T-wave amplitude in lead aVR becomes less negative, there was a progressive increase in mortality. The T wave in lead aVR provides prognostic information for risk stratification in HF patients with narrow QRS complexes.",
author = "Kentarou Okuda and Eiichi Watanabe and Kan Sano and Tomoharu Arakawa and Mayumi Yamamoto and Yoshihiro Sobue and Tatsushi Uchiyama and Yukio Ozaki",
year = "2011",
month = "7",
day = "1",
doi = "10.1111/j.1542-474X.2011.00439.x",
language = "English",
volume = "16",
pages = "250--257",
journal = "Annals of Noninvasive Electrocardiology",
issn = "1082-720X",
publisher = "Wiley-Blackwell",
number = "3",

}

Prognostic significance of T-wave amplitude in lead aVR in heart failure patients with narrow QRS complexes. / Okuda, Kentarou; Watanabe, Eiichi; Sano, Kan; Arakawa, Tomoharu; Yamamoto, Mayumi; Sobue, Yoshihiro; Uchiyama, Tatsushi; Ozaki, Yukio.

:: Annals of Noninvasive Electrocardiology, 巻 16, 番号 3, 01.07.2011, p. 250-257.

研究成果: Article

TY - JOUR

T1 - Prognostic significance of T-wave amplitude in lead aVR in heart failure patients with narrow QRS complexes

AU - Okuda, Kentarou

AU - Watanabe, Eiichi

AU - Sano, Kan

AU - Arakawa, Tomoharu

AU - Yamamoto, Mayumi

AU - Sobue, Yoshihiro

AU - Uchiyama, Tatsushi

AU - Ozaki, Yukio

PY - 2011/7/1

Y1 - 2011/7/1

N2 - Background: Prolonged duration of the QRS complex is a prognostic marker in patients with heart failure (HF), whereas electrocadiographic markers in HF with narrow QRS complex remain unclear. We evaluated the prognostic value of the T-wave amplitude in lead aVR in HF patients with narrow QRS complexes. Methods: We examined 331 patients who were admitted to our hospital for worsening HF (68 ± 15 years, mean ± standard deviation) from January 2000 to October 2004 who had sinus rhythm and QRS complex <120 ms. The patients were categorized into three groups according to the peak T-wave amplitude from baseline in lead aVR: negative (<-0.1 mV; n = 209, 63%), flat (-0.1-0.1 mV; n = 64, 19%), and positive (>0.1 mV; n = 58, 18%). Results: During a mean follow-up of 33 months, 113 (34%) patients had all-cause death, the primary end point. After adjusting for clinical covariates, flat T wave (hazard ratio [HR] 1.86, 95% confidence interval [CI] 1.42-2.46), and positive T wave (HR 6.76, 95% CI 3.92-11.8) were independent predictors of mortality, when negative T wave was considered a reference. Conclusions: As the peak T-wave amplitude in lead aVR becomes less negative, there was a progressive increase in mortality. The T wave in lead aVR provides prognostic information for risk stratification in HF patients with narrow QRS complexes.

AB - Background: Prolonged duration of the QRS complex is a prognostic marker in patients with heart failure (HF), whereas electrocadiographic markers in HF with narrow QRS complex remain unclear. We evaluated the prognostic value of the T-wave amplitude in lead aVR in HF patients with narrow QRS complexes. Methods: We examined 331 patients who were admitted to our hospital for worsening HF (68 ± 15 years, mean ± standard deviation) from January 2000 to October 2004 who had sinus rhythm and QRS complex <120 ms. The patients were categorized into three groups according to the peak T-wave amplitude from baseline in lead aVR: negative (<-0.1 mV; n = 209, 63%), flat (-0.1-0.1 mV; n = 64, 19%), and positive (>0.1 mV; n = 58, 18%). Results: During a mean follow-up of 33 months, 113 (34%) patients had all-cause death, the primary end point. After adjusting for clinical covariates, flat T wave (hazard ratio [HR] 1.86, 95% confidence interval [CI] 1.42-2.46), and positive T wave (HR 6.76, 95% CI 3.92-11.8) were independent predictors of mortality, when negative T wave was considered a reference. Conclusions: As the peak T-wave amplitude in lead aVR becomes less negative, there was a progressive increase in mortality. The T wave in lead aVR provides prognostic information for risk stratification in HF patients with narrow QRS complexes.

UR - http://www.scopus.com/inward/record.url?scp=79960609852&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79960609852&partnerID=8YFLogxK

U2 - 10.1111/j.1542-474X.2011.00439.x

DO - 10.1111/j.1542-474X.2011.00439.x

M3 - Article

C2 - 21762252

AN - SCOPUS:79960609852

VL - 16

SP - 250

EP - 257

JO - Annals of Noninvasive Electrocardiology

JF - Annals of Noninvasive Electrocardiology

SN - 1082-720X

IS - 3

ER -