Protein phosphorylation and mechanism of action of tumor-promoting phorbol esters.

U. Kikkawa, K. Kaibuchi, M. Castagna, J. Yamanishi, K. Sano, Y. Tanaka, R. Miyake, Y. Takai, Y. Nishizuka

研究成果: ジャーナルへの寄稿学術論文査読

25 被引用数 (Scopus)

抄録

The phorbol ester TPA may be intercalated into the membrane phospholipid bilayer and selectively binds to every molecule of C-kinase in exhibiting its full enzymatic activity. Available evidence suggests that C-kinase is the receptive protein of this tumor promoter, and the results presented seem to provide clues for clarifying the mechanism of controlling cell growth and differentiation.

本文言語英語
ページ(範囲)437-442
ページ数6
ジャーナルAdvances in cyclic nucleotide and protein phosphorylation research
17
出版ステータス出版済み - 1984

All Science Journal Classification (ASJC) codes

  • 医学一般

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