Protein phosphorylation and mechanism of action of tumor-promoting phorbol esters.

U. Kikkawa; K. Kaibuchi; M. Castagna; J. Yamanishi; K. Sano; Y. Tanaka; R. Miyake; Y. Takai; Y. Nishizuka

Protein phosphorylation and mechanism of action of tumor-promoting phorbol esters.

U. Kikkawa
, K. Kaibuchi
, M. Castagna
, J. Yamanishi
, K. Sano
, Y. Tanaka
, R. Miyake
, Y. Takai
, Y. Nishizuka

神経・腫瘍のシグナル解析プロジェクト研究

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

25 被引用数 (Scopus)

抄録

The phorbol ester TPA may be intercalated into the membrane phospholipid bilayer and selectively binds to every molecule of C-kinase in exhibiting its full enzymatic activity. Available evidence suggests that C-kinase is the receptive protein of this tumor promoter, and the results presented seem to provide clues for clarifying the mechanism of controlling cell growth and differentiation.

本文言語	英語
ページ（範囲）	437-442
ページ数	6
ジャーナル	Advances in cyclic nucleotide and protein phosphorylation research
巻	17
出版ステータス	出版済み - 1984

All Science Journal Classification (ASJC) codes

医学一般

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引用スタイル

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title = "Protein phosphorylation and mechanism of action of tumor-promoting phorbol esters.",

abstract = "The phorbol ester TPA may be intercalated into the membrane phospholipid bilayer and selectively binds to every molecule of C-kinase in exhibiting its full enzymatic activity. Available evidence suggests that C-kinase is the receptive protein of this tumor promoter, and the results presented seem to provide clues for clarifying the mechanism of controlling cell growth and differentiation.",

author = "U. Kikkawa and K. Kaibuchi and M. Castagna and J. Yamanishi and K. Sano and Y. Tanaka and R. Miyake and Y. Takai and Y. Nishizuka",

year = "1984",

language = "English",

volume = "17",

pages = "437--442",

journal = "Advances in cyclic nucleotide and protein phosphorylation research",

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T1 - Protein phosphorylation and mechanism of action of tumor-promoting phorbol esters.

AU - Kikkawa, U.

AU - Kaibuchi, K.

AU - Castagna, M.

AU - Yamanishi, J.

AU - Sano, K.

AU - Tanaka, Y.

AU - Miyake, R.

AU - Takai, Y.

AU - Nishizuka, Y.

PY - 1984

Y1 - 1984

N2 - The phorbol ester TPA may be intercalated into the membrane phospholipid bilayer and selectively binds to every molecule of C-kinase in exhibiting its full enzymatic activity. Available evidence suggests that C-kinase is the receptive protein of this tumor promoter, and the results presented seem to provide clues for clarifying the mechanism of controlling cell growth and differentiation.

AB - The phorbol ester TPA may be intercalated into the membrane phospholipid bilayer and selectively binds to every molecule of C-kinase in exhibiting its full enzymatic activity. Available evidence suggests that C-kinase is the receptive protein of this tumor promoter, and the results presented seem to provide clues for clarifying the mechanism of controlling cell growth and differentiation.

UR - https://www.scopus.com/pages/publications/0021314379

UR - https://www.scopus.com/pages/publications/0021314379#tab=citedBy

M3 - Article

C2 - 6328930

AN - SCOPUS:0021314379

SN - 0747-7767

VL - 17

SP - 437

EP - 442

JO - Advances in cyclic nucleotide and protein phosphorylation research

JF - Advances in cyclic nucleotide and protein phosphorylation research

ER -

Protein phosphorylation and mechanism of action of tumor-promoting phorbol esters.

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All Science Journal Classification (ASJC) codes

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