Quality control for clinical islet transplantation: Organ procurement and preservation, the islet processing facility, isolation, and potency tests

Toshiyuki Yamamoto, Akihiko Horiguchi, Masahiro Ito, Hideo Nagata, Hirohito Ichii, Camillo Ricordi, Shuichi Miyakawa

研究成果: Review article査読

27 被引用数 (Scopus)

抄録

Pancreatic islet transplantation has become one of the ideal treatments for patients with type 1 diabetes mellitus due to improvements in isolation techniques and immunosuppression regimens. In order to ensure the safety and rights of patients, isolated islets need to meet the criteria for regulation as both a biological product and a drug product. For the constant success of transplantation, therefore, all investigators involved in clinical islet transplantation must strive to ensure the safety, purity, and potency of islets in all the phases of clinical islet isolation and transplantation. In this review, we summarize the quality control for clinical islet isolation and transplantation, and the latest topics of pre-transplant islet assessment.

本文言語English
ページ(範囲)131-136
ページ数6
ジャーナルJournal of Hepato-Biliary-Pancreatic Surgery
16
2
DOI
出版ステータスPublished - 2009

All Science Journal Classification (ASJC) codes

  • Surgery
  • Hepatology

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