Radiation Therapy for Uterine Cervix Cancer: Importance of evaluation of pre-treatment tumor size with MR imaging

Masahiro Sasaoka, Yoshihito Nomoto, Kazufusa Shoji, Shigeki Kobayashi, Shun Toyota, Tsuyoshi Nakagawa

研究成果: Article査読

2 被引用数 (Scopus)

抄録

From May 1992 through December 1995, a total of 42 patients with previously untreated squamous cell carcinoma of the uterine cervix were treated by using middle-dose-rate intracavitary therapy, and their previously treated local tumor volume was evaluated with MRI. According to the staging of FIGO, 2 patients were classified as Stage IB, 2 as IIA, 18 as IIB, 1 as IIIA, 14 as IIIB, 2 as IVA and 3 as IVB. Cumulative 3-year survival rates were 89% in Stage IIB and 54% in IIIB. 3-year local control rates were 100% in Stage IIB and 67% in IIIB. On the other hand, the cumulative survival rate for the local control group in all stages was 100% at 2 years and 82% at 3 years. For the pelvic failure group it was 41% at 2 years. All of those in the pelvic failure group had bulky local tumor sizes of more than 60mm in the previous treatment MRI study. The 3-year cumulative survival rate and local control rate for tumors less than 60mm were 84% and 100%, but for tumors over 60 mm the respective rates were 45% and 33% (p < 0.01). The a results showed that the group with pretreatment of local tumors over 60 mm on MRI had a poor outcome. We concluded that pretreatment tumor volume is an important factor in prognosis and the evaluation of pretreatment tumor volume by imaging study (MRI) is necessary.

本文言語English
ページ(範囲)505-509
ページ数5
ジャーナルNippon Acta Radiologica
57
8
出版ステータスPublished - 01-12-1997
外部発表はい

All Science Journal Classification (ASJC) codes

  • 放射線学、核医学およびイメージング
  • 腫瘍学

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