Rapid Diagnostic Test Value and Implementation in Antimicrobial Stewardship Across Low-to-Middle and High-Income Countries: A Mixed-Methods Review

Luke S.P. Moore, Maria Virginia Villegas, Eric Wenzler, Timothy M. Rawson, Rita O. Oladele, Yohei Doi, Anucha Apisarnthanarak

研究成果: ジャーナルへの寄稿コメント/討論査読

4 被引用数 (Scopus)

抄録

Despite technological advancements in infectious disease rapid diagnostic tests (RDTs) and use to direct therapy at the per-patient level, RDT utilisation in antimicrobial stewardship programmes (ASPs) is variable across low-to-middle income and high-income countries. Key insights from a panel of seven infectious disease experts from Colombia, Japan, Nigeria, Thailand, the UK, and the USA, combined with evidence from a literature review, were used to assess the value of RDTs in ASPs. From this, a value framework is proposed which aims to define the benefits of RDT use in ASPs, separate from per-patient benefits. Expert insights highlight that, to realise the value of RDTs within ASPs, effective implementation is key; actionable advice for choosing an RDT is proposed. Experts advocate the inclusion of RDTs in the World Health Organization Model List of essential in vitro diagnostics and in iterative development of national action plans.

本文言語英語
ページ(範囲)1445-1463
ページ数19
ジャーナルInfectious Diseases and Therapy
12
6
DOI
出版ステータス出版済み - 06-2023

All Science Journal Classification (ASJC) codes

  • 微生物学(医療)
  • 感染症

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