TY - JOUR
T1 - Reactivation of herpesvirus type 6 in children receiving bone marrow transplants for leukemia
AU - Asano, Yoshizo
AU - Yoshikawa, Tetsushi
AU - Suga, Sadao
AU - Nakashima, Toshihiko
AU - Yazaki, Takehiko
AU - Fukuda, Minoru
AU - Kojima, Seiji
AU - Matsuyama, Takaharu
PY - 1991/2/28
Y1 - 1991/2/28
N2 - To the Editor: Human herpesvirus Type 6 (herpesvirus 6) has been isolated from peripheral-blood mononuclear cells of the liver1 and kidney2 of transplant recipients. However, the clinical importance of infection with this virus after organ transplantation is unknown. We report here on infection with herpesvirus 6 in three children with leukemia after bone marrow transplantation. Their clinical and virologic features are summarized in Table 1. All three children had received bone marrow from HLA-matched siblings. Herpesvirus 6 was isolated by coculturing peripheral-blood mononuclear cells from the donors and recipients with phytohemagglutinin-stimulated cord-blood mononuclear cells.3 The virus was isolated from the blood of. .
AB - To the Editor: Human herpesvirus Type 6 (herpesvirus 6) has been isolated from peripheral-blood mononuclear cells of the liver1 and kidney2 of transplant recipients. However, the clinical importance of infection with this virus after organ transplantation is unknown. We report here on infection with herpesvirus 6 in three children with leukemia after bone marrow transplantation. Their clinical and virologic features are summarized in Table 1. All three children had received bone marrow from HLA-matched siblings. Herpesvirus 6 was isolated by coculturing peripheral-blood mononuclear cells from the donors and recipients with phytohemagglutinin-stimulated cord-blood mononuclear cells.3 The virus was isolated from the blood of. .
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U2 - 10.1056/NEJM199102283240915
DO - 10.1056/NEJM199102283240915
M3 - Letter
C2 - 1846942
AN - SCOPUS:0026028239
SN - 0028-4793
VL - 324
SP - 634
EP - 635
JO - New England Journal of Medicine
JF - New England Journal of Medicine
IS - 9
ER -