Reduced intensity conditioning in allogeneic stem cell transplantation for AML with Down syndrome

Hideki Muramatsu; Hirotoshi Sakaguchi; Takashi Taga; Ken Tabuchi; Souichi Adachi; Masami Inoue; Toshiyuki Kitoh; Aiko Suminoe; Hiromasa Yabe; Eichi Azuma; Yoko Shioda; Atsushi Ogawa; Akitoshi Kinoshita; Hisato Kigasawa; Yuko Osugi; Kazutoshi Koike; Keisei Kawa; Koji Kato; Yoshiko Atsuta; Kazuko Kudo

doi:10.1002/pbc.24883

Reduced intensity conditioning in allogeneic stem cell transplantation for AML with Down syndrome

Hideki Muramatsu, Hirotoshi Sakaguchi, Takashi Taga, Ken Tabuchi, Souichi Adachi, Masami Inoue, Toshiyuki Kitoh, Aiko Suminoe, Hiromasa Yabe, Eichi Azuma, Yoko Shioda, Atsushi Ogawa, Akitoshi Kinoshita, Hisato Kigasawa, Yuko Osugi, Kazutoshi Koike, Keisei Kawa, Koji Kato, Yoshiko Atsuta, Kazuko Kudo

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

11 被引用数 (Scopus)

抄録

Allogeneic hematopoietic stem cell transplantation (HSCT) has not been widely used in patients with acute myeloid leukemia (AML) and Down syndrome (DS) due to fear of transplantation-related toxicity. A retrospective analysis of the outcome of allogeneic HSCT was conducted in 15 patients with AML and DS. The five patients transplanted with the reduced intensity conditioning (4 in complete remission (CR) and 1 in non-CR) had a significantly better survival rate than 10 patients transplanted with a conventional conditioning (4 in CR and 6 in non-CR) (3-year EFS (95% confidence interval): 80.0% (20.4-96.9%) vs. 10.0% (0.6%-35.8%), P=0.039). Pediatr Blood Cancer 2014;61:925-927.

本文言語	英語
ページ（範囲）	925-927
ページ数	3
ジャーナル	Pediatric Blood and Cancer
巻	61
号	5
DOI	https://doi.org/10.1002/pbc.24883
出版ステータス	出版済み - 05-2014
外部発表	はい

All Science Journal Classification (ASJC) codes

小児科学、周産期医学および子どもの健康
血液学
腫瘍学

UN SDG

この成果は、次の持続可能な開発目標に貢献しています

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10.1002/pbc.24883

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引用スタイル

Muramatsu, H., Sakaguchi, H., Taga, T., Tabuchi, K., Adachi, S., Inoue, M., Kitoh, T., Suminoe, A., Yabe, H., Azuma, E., Shioda, Y., Ogawa, A., Kinoshita, A., Kigasawa, H., Osugi, Y., Koike, K., Kawa, K., Kato, K., Atsuta, Y., & Kudo, K. (2014). Reduced intensity conditioning in allogeneic stem cell transplantation for AML with Down syndrome. Pediatric Blood and Cancer, 61(5), 925-927. https://doi.org/10.1002/pbc.24883

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title = "Reduced intensity conditioning in allogeneic stem cell transplantation for AML with Down syndrome",

abstract = "Allogeneic hematopoietic stem cell transplantation (HSCT) has not been widely used in patients with acute myeloid leukemia (AML) and Down syndrome (DS) due to fear of transplantation-related toxicity. A retrospective analysis of the outcome of allogeneic HSCT was conducted in 15 patients with AML and DS. The five patients transplanted with the reduced intensity conditioning (4 in complete remission (CR) and 1 in non-CR) had a significantly better survival rate than 10 patients transplanted with a conventional conditioning (4 in CR and 6 in non-CR) (3-year EFS (95% confidence interval): 80.0% (20.4-96.9%) vs. 10.0% (0.6%-35.8%), P=0.039). Pediatr Blood Cancer 2014;61:925-927.",

author = "Hideki Muramatsu and Hirotoshi Sakaguchi and Takashi Taga and Ken Tabuchi and Souichi Adachi and Masami Inoue and Toshiyuki Kitoh and Aiko Suminoe and Hiromasa Yabe and Eichi Azuma and Yoko Shioda and Atsushi Ogawa and Akitoshi Kinoshita and Hisato Kigasawa and Yuko Osugi and Kazutoshi Koike and Keisei Kawa and Koji Kato and Yoshiko Atsuta and Kazuko Kudo",

year = "2014",

month = may,

doi = "10.1002/pbc.24883",

language = "English",

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pages = "925--927",

journal = "Pediatric Blood and Cancer",

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}

Muramatsu, H, Sakaguchi, H, Taga, T, Tabuchi, K, Adachi, S, Inoue, M, Kitoh, T, Suminoe, A, Yabe, H, Azuma, E, Shioda, Y, Ogawa, A, Kinoshita, A, Kigasawa, H, Osugi, Y, Koike, K, Kawa, K, Kato, K, Atsuta, Y & Kudo, K 2014, 'Reduced intensity conditioning in allogeneic stem cell transplantation for AML with Down syndrome', Pediatric Blood and Cancer, vol. 61, no. 5, pp. 925-927. https://doi.org/10.1002/pbc.24883

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T1 - Reduced intensity conditioning in allogeneic stem cell transplantation for AML with Down syndrome

AU - Muramatsu, Hideki

AU - Sakaguchi, Hirotoshi

AU - Taga, Takashi

AU - Tabuchi, Ken

AU - Adachi, Souichi

AU - Inoue, Masami

AU - Kitoh, Toshiyuki

AU - Suminoe, Aiko

AU - Yabe, Hiromasa

AU - Azuma, Eichi

AU - Shioda, Yoko

AU - Ogawa, Atsushi

AU - Kinoshita, Akitoshi

AU - Kigasawa, Hisato

AU - Osugi, Yuko

AU - Koike, Kazutoshi

AU - Kawa, Keisei

AU - Kato, Koji

AU - Atsuta, Yoshiko

AU - Kudo, Kazuko

PY - 2014/5

Y1 - 2014/5

N2 - Allogeneic hematopoietic stem cell transplantation (HSCT) has not been widely used in patients with acute myeloid leukemia (AML) and Down syndrome (DS) due to fear of transplantation-related toxicity. A retrospective analysis of the outcome of allogeneic HSCT was conducted in 15 patients with AML and DS. The five patients transplanted with the reduced intensity conditioning (4 in complete remission (CR) and 1 in non-CR) had a significantly better survival rate than 10 patients transplanted with a conventional conditioning (4 in CR and 6 in non-CR) (3-year EFS (95% confidence interval): 80.0% (20.4-96.9%) vs. 10.0% (0.6%-35.8%), P=0.039). Pediatr Blood Cancer 2014;61:925-927.

AB - Allogeneic hematopoietic stem cell transplantation (HSCT) has not been widely used in patients with acute myeloid leukemia (AML) and Down syndrome (DS) due to fear of transplantation-related toxicity. A retrospective analysis of the outcome of allogeneic HSCT was conducted in 15 patients with AML and DS. The five patients transplanted with the reduced intensity conditioning (4 in complete remission (CR) and 1 in non-CR) had a significantly better survival rate than 10 patients transplanted with a conventional conditioning (4 in CR and 6 in non-CR) (3-year EFS (95% confidence interval): 80.0% (20.4-96.9%) vs. 10.0% (0.6%-35.8%), P=0.039). Pediatr Blood Cancer 2014;61:925-927.

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JO - Pediatric Blood and Cancer

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Reduced intensity conditioning in allogeneic stem cell transplantation for AML with Down syndrome

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All Science Journal Classification (ASJC) codes

UN SDG

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