Reference ranges for serum cystatin C measurements in Japanese children by using 4 automated assays

Nahoko Yata, Osamu Uemura, Masataka Honda, Takeshi Matsuyama, Kenji Ishikura, Hiroshi Hataya, Takuhito Nagai, Yohei Ikezumi, Naoya Fujita, Shuichi Ito, Kazumoto Iijima, Mari Saito, Tetsuji Keneko, Teruo Kitagawa

研究成果: Article

8 引用 (Scopus)

抄録

Objective: The data available on reference ranges for cystatin C in children are limited, and there are discrepancies among the available data. The aim of this study was to describe the reference ranges for cystatin C in Japanese children by using 4 automated assays. Methods: Serum cystatin C levels were measured in 1128 Japanese children aged 3 month to 16 years without kidney disease. We calculated age-, gender-, race- and assay-specific cystatin C ranges. Results: For all 4 assays, the median serum cystatin C levels were raised in term infants compared with older children and decreased by the first 2 years. The median serum cystatin C levels remained constant throughout up to the age of 14 years and decreased in children aged 15-16 years. The median serum cystatin C levels in children aged 12-16 years were slightly higher in males than in females. Assay-specific differences were also observed in the levels of serum cystatin C measured. Conclusion: Age-, gender-, race- and assay-specific ranges for serum cystatin C should be used as another tool to assess kidney function in children.

元の言語English
ページ(範囲)872-876
ページ数5
ジャーナルClinical and Experimental Nephrology
17
発行部数6
DOI
出版物ステータスPublished - 01-12-2013

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Cystatin C
Reference Values
Serum
Kidney Diseases
Kidney

All Science Journal Classification (ASJC) codes

  • Physiology
  • Nephrology
  • Physiology (medical)

これを引用

Yata, N., Uemura, O., Honda, M., Matsuyama, T., Ishikura, K., Hataya, H., ... Kitagawa, T. (2013). Reference ranges for serum cystatin C measurements in Japanese children by using 4 automated assays. Clinical and Experimental Nephrology, 17(6), 872-876. https://doi.org/10.1007/s10157-013-0784-x
Yata, Nahoko ; Uemura, Osamu ; Honda, Masataka ; Matsuyama, Takeshi ; Ishikura, Kenji ; Hataya, Hiroshi ; Nagai, Takuhito ; Ikezumi, Yohei ; Fujita, Naoya ; Ito, Shuichi ; Iijima, Kazumoto ; Saito, Mari ; Keneko, Tetsuji ; Kitagawa, Teruo. / Reference ranges for serum cystatin C measurements in Japanese children by using 4 automated assays. :: Clinical and Experimental Nephrology. 2013 ; 巻 17, 番号 6. pp. 872-876.
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abstract = "Objective: The data available on reference ranges for cystatin C in children are limited, and there are discrepancies among the available data. The aim of this study was to describe the reference ranges for cystatin C in Japanese children by using 4 automated assays. Methods: Serum cystatin C levels were measured in 1128 Japanese children aged 3 month to 16 years without kidney disease. We calculated age-, gender-, race- and assay-specific cystatin C ranges. Results: For all 4 assays, the median serum cystatin C levels were raised in term infants compared with older children and decreased by the first 2 years. The median serum cystatin C levels remained constant throughout up to the age of 14 years and decreased in children aged 15-16 years. The median serum cystatin C levels in children aged 12-16 years were slightly higher in males than in females. Assay-specific differences were also observed in the levels of serum cystatin C measured. Conclusion: Age-, gender-, race- and assay-specific ranges for serum cystatin C should be used as another tool to assess kidney function in children.",
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Yata, N, Uemura, O, Honda, M, Matsuyama, T, Ishikura, K, Hataya, H, Nagai, T, Ikezumi, Y, Fujita, N, Ito, S, Iijima, K, Saito, M, Keneko, T & Kitagawa, T 2013, 'Reference ranges for serum cystatin C measurements in Japanese children by using 4 automated assays', Clinical and Experimental Nephrology, 巻. 17, 番号 6, pp. 872-876. https://doi.org/10.1007/s10157-013-0784-x

Reference ranges for serum cystatin C measurements in Japanese children by using 4 automated assays. / Yata, Nahoko; Uemura, Osamu; Honda, Masataka; Matsuyama, Takeshi; Ishikura, Kenji; Hataya, Hiroshi; Nagai, Takuhito; Ikezumi, Yohei; Fujita, Naoya; Ito, Shuichi; Iijima, Kazumoto; Saito, Mari; Keneko, Tetsuji; Kitagawa, Teruo.

:: Clinical and Experimental Nephrology, 巻 17, 番号 6, 01.12.2013, p. 872-876.

研究成果: Article

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T1 - Reference ranges for serum cystatin C measurements in Japanese children by using 4 automated assays

AU - Yata, Nahoko

AU - Uemura, Osamu

AU - Honda, Masataka

AU - Matsuyama, Takeshi

AU - Ishikura, Kenji

AU - Hataya, Hiroshi

AU - Nagai, Takuhito

AU - Ikezumi, Yohei

AU - Fujita, Naoya

AU - Ito, Shuichi

AU - Iijima, Kazumoto

AU - Saito, Mari

AU - Keneko, Tetsuji

AU - Kitagawa, Teruo

PY - 2013/12/1

Y1 - 2013/12/1

N2 - Objective: The data available on reference ranges for cystatin C in children are limited, and there are discrepancies among the available data. The aim of this study was to describe the reference ranges for cystatin C in Japanese children by using 4 automated assays. Methods: Serum cystatin C levels were measured in 1128 Japanese children aged 3 month to 16 years without kidney disease. We calculated age-, gender-, race- and assay-specific cystatin C ranges. Results: For all 4 assays, the median serum cystatin C levels were raised in term infants compared with older children and decreased by the first 2 years. The median serum cystatin C levels remained constant throughout up to the age of 14 years and decreased in children aged 15-16 years. The median serum cystatin C levels in children aged 12-16 years were slightly higher in males than in females. Assay-specific differences were also observed in the levels of serum cystatin C measured. Conclusion: Age-, gender-, race- and assay-specific ranges for serum cystatin C should be used as another tool to assess kidney function in children.

AB - Objective: The data available on reference ranges for cystatin C in children are limited, and there are discrepancies among the available data. The aim of this study was to describe the reference ranges for cystatin C in Japanese children by using 4 automated assays. Methods: Serum cystatin C levels were measured in 1128 Japanese children aged 3 month to 16 years without kidney disease. We calculated age-, gender-, race- and assay-specific cystatin C ranges. Results: For all 4 assays, the median serum cystatin C levels were raised in term infants compared with older children and decreased by the first 2 years. The median serum cystatin C levels remained constant throughout up to the age of 14 years and decreased in children aged 15-16 years. The median serum cystatin C levels in children aged 12-16 years were slightly higher in males than in females. Assay-specific differences were also observed in the levels of serum cystatin C measured. Conclusion: Age-, gender-, race- and assay-specific ranges for serum cystatin C should be used as another tool to assess kidney function in children.

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U2 - 10.1007/s10157-013-0784-x

DO - 10.1007/s10157-013-0784-x

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EP - 876

JO - Clinical and Experimental Nephrology

JF - Clinical and Experimental Nephrology

SN - 1342-1751

IS - 6

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