Regeneration-based therapies for spinal cord injuries

Hideyuki Okano; Shinjiro Kaneko; Seiji Okada; Akio Iwanami; Masaya Nakamura; Yoshiaki Toyama

doi:10.1016/j.neuint.2007.04.013

Regeneration-based therapies for spinal cord injuries

Hideyuki Okano
, Shinjiro Kaneko
, Seiji Okada
, Akio Iwanami
, Masaya Nakamura
, Yoshiaki Toyama

研究成果: ジャーナルへの寄稿 › 総説 › 査読

26 被引用数 (Scopus)

抄録

Although it has been long believed that the damaged central nervous system does not regenerate upon injury, there is an emerging hope for regeneration-based therapy of the damaged central nervous system (CNS) due to the progress of developmental biology and regenerative medicine including stem cell biology. In this review, we have summarized recent studies aimed at the development of regeneration-based therapeutic approaches for spinal cord injuries, including therapy with anti-inflammatory cytokines, transplantation of neural stem/precursor cells and induction of axonal regeneration.

本文言語	英語
ページ（範囲）	68-73
ページ数	6
ジャーナル	Neurochemistry International
巻	51
号	2-4 SPEC. ISS.
DOI	https://doi.org/10.1016/j.neuint.2007.04.013
出版ステータス	出版済み - 07-2007
外部発表	はい

All Science Journal Classification (ASJC) codes

細胞および分子神経科学
細胞生物学

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10.1016/j.neuint.2007.04.013

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引用スタイル

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title = "Regeneration-based therapies for spinal cord injuries",

abstract = "Although it has been long believed that the damaged central nervous system does not regenerate upon injury, there is an emerging hope for regeneration-based therapy of the damaged central nervous system (CNS) due to the progress of developmental biology and regenerative medicine including stem cell biology. In this review, we have summarized recent studies aimed at the development of regeneration-based therapeutic approaches for spinal cord injuries, including therapy with anti-inflammatory cytokines, transplantation of neural stem/precursor cells and induction of axonal regeneration.",

author = "Hideyuki Okano and Shinjiro Kaneko and Seiji Okada and Akio Iwanami and Masaya Nakamura and Yoshiaki Toyama",

note = "Funding Information: We are grateful to the members of the Okano Laboratory for their comments on the manuscript. This work was supported by a grant from Solution-Oriented Research for Science and Technology (SORST), Japan Science and Technology Agency (JST) and those from the Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan; the Japan Science and Technology Corporation (JST)",

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T1 - Regeneration-based therapies for spinal cord injuries

AU - Okano, Hideyuki

AU - Kaneko, Shinjiro

AU - Okada, Seiji

AU - Iwanami, Akio

AU - Nakamura, Masaya

AU - Toyama, Yoshiaki

N1 - Funding Information: We are grateful to the members of the Okano Laboratory for their comments on the manuscript. This work was supported by a grant from Solution-Oriented Research for Science and Technology (SORST), Japan Science and Technology Agency (JST) and those from the Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan; the Japan Science and Technology Corporation (JST)

PY - 2007/7

Y1 - 2007/7

N2 - Although it has been long believed that the damaged central nervous system does not regenerate upon injury, there is an emerging hope for regeneration-based therapy of the damaged central nervous system (CNS) due to the progress of developmental biology and regenerative medicine including stem cell biology. In this review, we have summarized recent studies aimed at the development of regeneration-based therapeutic approaches for spinal cord injuries, including therapy with anti-inflammatory cytokines, transplantation of neural stem/precursor cells and induction of axonal regeneration.

AB - Although it has been long believed that the damaged central nervous system does not regenerate upon injury, there is an emerging hope for regeneration-based therapy of the damaged central nervous system (CNS) due to the progress of developmental biology and regenerative medicine including stem cell biology. In this review, we have summarized recent studies aimed at the development of regeneration-based therapeutic approaches for spinal cord injuries, including therapy with anti-inflammatory cytokines, transplantation of neural stem/precursor cells and induction of axonal regeneration.

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U2 - 10.1016/j.neuint.2007.04.013

DO - 10.1016/j.neuint.2007.04.013

M3 - Review article

C2 - 17544171

AN - SCOPUS:34547459568

SN - 0197-0186

VL - 51

SP - 68

EP - 73

JO - Neurochemistry International

JF - Neurochemistry International

IS - 2-4 SPEC. ISS.

ER -

Regeneration-based therapies for spinal cord injuries

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