Regulation of neuronal migration, an emerging topic in autism spectrum disorders

Orly Reiner, Eyal Karzbrun, Aditya Kshirsagar, Kozo Kaibuchi

研究成果: Article査読

59 被引用数 (Scopus)

抄録

Autism spectrum disorders (ASD) encompass a group of neurodevelopmental diseases that demonstrate strong heritability, however, the inheritance is not simple and many genes have been associated with these disorders. ASD is regarded as a neurodevelopmental disorder, and abnormalities at different developmental stages are part of the disease etiology. This review provides a general background on neuronal migration during brain development and discusses recent advancements in the field connecting ASD and aberrant neuronal migration. We propose that neuronal migration impairment may be an important common pathophysiology in autism spectrum disorders (ASD). This review provides a general background on neuronal migration during brain development and discusses recent advancements in the field connecting ASD and aberrant neuronal migration. We propose that neuronal migration impairment may be an important common pathophysiology in autism spectrum disorders (ASD). This review provides a general background on neuronal migration during brain development and discusses recent advancements in the field connecting ASD and aberrant neuronal migration.

本文言語English
ページ(範囲)440-456
ページ数17
ジャーナルJournal of neurochemistry
136
3
DOI
出版ステータスPublished - 01-02-2016
外部発表はい

All Science Journal Classification (ASJC) codes

  • 生化学
  • 細胞および分子神経科学

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