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Relationship of Soluble Fas with Body Mass Index in Healthy Japanese Adults

  • Akiko Tamakoshi
  • , Koji Suzuki
  • , Yingsong Lin
  • , Yoshinori Ito
  • , Kiyoko Yagyu
  • , Shogo Kikuchi
  • , Yoshiyuki Watanabe
  • , Yutaka Inaba
  • , Kazuo Tajima
  • , Kei Nakachi
  • , Mitsuru Mori
  • , Fumio Sakauchi
  • , Yutaka Motohashi
  • , Ichiro Tsuji
  • , Yosikazu Nakamura
  • , Hiroyasu Iso
  • , Haruo Mikami
  • , Michiko Kurosawa
  • , Yoshiharu Hoshiyama
  • , Naohito Tanabe
  • Koji Tamakoshi, Kenji Wakai, Shinkan Tokudome, Shuji Hashimoto, Shogo Kikuchi, Yasuhiko Wada, Takashi Kawamura, Yoshiyuki Watanabe, Kotaro Ozasa, Tsuneharu Miki, Chigusa Date, Kiyomi Sakata, Yoichi Kurozawa, Takesumi Yoshimura, Yoshihisa Fujino, Akira Shibata, Naoyuki Okamoto, Hideo Shio

研究成果: ジャーナルへの寄稿学術論文査読

抄録

Recent studies have linked elevated serum sFas levels to atherosclerotic disease among patients. Confirming an association between obesity and serum sFas levels in healthy subjects would facilitate our understanding of obesity and its related disorders. We therefore analyzed serum sFas levels of 8,541 subjects selected as controls for a nested case-control study within the JACC Study. Body mass index (BMI) was calculated as the indicator of obesity based on self-reported height and weight. We found a statistically significant positive association between serum sFas levels and BMI among our apparently healthy subjects. Our result suggests that serum sFas rises to down-regulate increased apoptosis in atherogenesis processes caused by obesity.

本文言語英語
ページ(範囲)41-44
ページ数4
ジャーナルAsian Pacific Journal of Cancer Prevention
10
SUPPL.1
出版ステータス出版済み - 12-2009

UN SDG

この成果は、次の持続可能な開発目標に貢献しています

  1. SDG 3 - すべての人に健康と福祉を
    SDG 3 すべての人に健康と福祉を

All Science Journal Classification (ASJC) codes

  • 疫学
  • 腫瘍学
  • 公衆衛生学、環境および労働衛生
  • 癌研究

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