Rho-family GTPases in cadherin-mediated cell-cell adhesion

Masaki Fukata, Kozo Kaibuchi

研究成果: Review article査読

340 被引用数 (Scopus)

抄録

Cell-cell adhesions are rearranged dynamically during tissue development and tumour metastasis. Recently, Rho-family GTPases, including RhoA, Rac1 and Cdc42, have emerged as key regulators of cadherin-mediated cell-cell adhesion. Following the identification and characterization of regulators and effectors of Rho GTPases, signal transduction pathways from cadherin to Rho GTPases and, in turn, from Rho GTPases to cadherin, are beginning to be clarified.

本文言語English
ページ(範囲)887-897
ページ数11
ジャーナルNature Reviews Molecular Cell Biology
2
12
DOI
出版ステータスPublished - 12-2001
外部発表はい

All Science Journal Classification (ASJC) codes

  • 分子生物学
  • 細胞生物学

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