Right ventricular end-diastolic volume in the postoperative care of cardiac surgery patients - A marker of the hemodynamic response to a fluid challenge

Yoshiyuki Tokuda, Min Ho Song, Norifumi Mabuchi, Akihiko Usui, Yuichi Ueda

研究成果: Article査読

2 被引用数 (Scopus)

抄録

Background: This study evaluated the right ventricular end-diastolic volume index (RVEDVI) as a marker of the hemodynamic response to a fluid challenge in the postoperative care of cardiac surgery patients. Methods and Results: Continuous RVEDVI and other hemodynamic parameters were analyzed during and after 17 fluid challenges with 480-500 ml colloids (5% albumin, fresh frozen plasma or 6% hydroxyethyl starch) given over 30-60min following cardiac surgery. Changes in stroke volume index (SVI) were assessed to indicate fluid responsiveness. Responders were defined as those who experienced a 10% or greater increase in SVI. Fluid challenges with simultaneous changing of vasoactive agents were excluded. Linear regression analysis between the percentage change in SVI and baseline RVEDVI revealed a statistically significant but weak correlation (r2=0.249; p=0.041). Although the baseline RVEDVI was higher in non-responders than in responders (112.4±6.1 vs 104.4±5.8ml/m2; p=0.05), there was a marked overlap of baseline RVEDVI values, which did not allow identification of the threshold value of RVEDVI discriminating responders. Conclusions: After cardiac surgery, RVEDVI reflected fluid responsiveness only to a limited degree. Patients should not be resuscitated to an absolute RVEDVI alone and empirical fluid challenge should still be required.

本文言語English
ページ(範囲)1408-1411
ページ数4
ジャーナルCirculation Journal
71
9
DOI
出版ステータスPublished - 2007
外部発表はい

All Science Journal Classification (ASJC) codes

  • 循環器および心血管医学

フィンガープリント

「Right ventricular end-diastolic volume in the postoperative care of cardiac surgery patients - A marker of the hemodynamic response to a fluid challenge」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル