Role of computational fluid dynamics for predicting delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage: Study protocol for a multicenter prospective study

CFD3 Study Group

研究成果: Chapter

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Background: Delayed cerebral ischemia (DCI) is a significant cause of morbidity and mortality after aneurysmal subarachnoid hemorrhage (SAH). Recently, we reported the possibility that computational fluid dynamics (CFD) could predict DCI in terms of the cross-sectional area and flow velocity of the ipsilateral extracranial internal carotid and distal parent arteries in a single-center retrospective study. Methods: This is a multicenter, prospective, cohort study. Patients with aneurysmal SAH will undergo CFD analyses using preoperative three-dimensional computed tomography angiography, and we will investigate hemodynamic features of cerebral arteries in an acute stage of SAH. Primary outcome measures will be CFD features in patients with subsequent occurrence of DCI. Secondary outcome measures will be CFD features in patients with subsequent occurrence of cerebral vasospasm and cerebral infarction and the relationships with eventual modified Rankin scale score at 3 months. Conclusions: The present protocol for a multicenter prospective study is expected to provide a novel diagnostic method to predict DCI before aneurysmal obliteration in an acute stage of SAH.

本文言語English
ホスト出版物のタイトルActa Neurochirurgica, Supplementum
出版社Springer-Verlag Wien
ページ161-164
ページ数4
DOI
出版ステータスPublished - 2020

出版物シリーズ

名前Acta Neurochirurgica, Supplementum
127
ISSN(印刷版)0065-1419
ISSN(電子版)2197-8395

All Science Journal Classification (ASJC) codes

  • Surgery
  • Clinical Neurology

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