Role of the endothelial pump in flap adhesion after laser in situ keratomileusis

Hiroko Bissen-Miyajima, Kunihiko Nakamura, Minako Kaido, Shigeto Shimmura, Kazuo Tsubota

研究成果: ジャーナルへの寄稿学術論文査読

11 被引用数 (Scopus)

抄録

Purpose: To investigate the role of the endothelial pump in the attachment of the corneal flap during the early period after laser in situ keratomileusis (LASIK). Setting: Department of Ophthalmology, Tokyo Dental College, Tokyo, Japan. Methods: The study comprised 30 porcine eyes. In all eyes, a corneal flap was made with a microkeratome. Five minutes after the flap was placed over the bed, the adhesion strength was measured with a load-testing machine. To inhibit the endothelial pump, ouabain was injected into the anterior chamber (10 eyes) or the endothelium was mechanically scraped (10 eyes). The control group included 10 eyes. Results: The load needed to lift the flap was significantly lower in the ouabain group (0.21 gram force [gf]; P<.01) and the endothelial scrape group (0.22 gf; P<.01) than in the control group (0.61 gf). Conclusion: The endothelial pump plays an important role in flap attachment in the early postoperative period after LASIK.

本文言語英語
ページ(範囲)1989-1992
ページ数4
ジャーナルJournal of Cataract and Refractive Surgery
30
9
DOI
出版ステータス出版済み - 09-2004
外部発表はい

All Science Journal Classification (ASJC) codes

  • 外科
  • 眼科学
  • 感覚系

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