抄録
The complementary DNA of a metabotropic glutamate receptor coupled to inositol phosphate/Ca2+ signal transduction has been cloned and characterized. This receptor shows no sequence similarity to conventional G protein-coupled receptors and has a unique structure with large hydrophilic sequences at both sides of seven putative membrane-spanning domains. Abundant expression of this messenger RNA is observed in neuronal cells in hippocampal dentate gyrus and CA2-3 and in cerebellar Purkinje cells, suggesting the importance of this receptor in specific hippocampal and cerebellar functions.
本文言語 | 英語 |
---|---|
ページ(範囲) | 760-765 |
ページ数 | 6 |
ジャーナル | Nature |
巻 | 349 |
号 | 6312 |
DOI | |
出版ステータス | 出版済み - 1991 |
外部発表 | はい |
All Science Journal Classification (ASJC) codes
- 一般