Serum albumin-adjusted glycated albumin as a better indicator of glycemic control in Type 2 diabetes mellitus patients with short duration of hemodialysis

Takahiro Yajima, Kumiko Yajima, Makoto Hayashi, Hiroshi Takahashi, Keigo Yasuda

研究成果: Article査読

11 被引用数 (Scopus)

抄録

Aims Serum albumin-adjusted glycated albumin (adjusted GA) is reportedly a better predictor of mortality than GA in patients with Type 2 diabetes mellitus (T2DM) on hemodialysis (HD). We compared how accurately GA and adjusted GA reflected glycemic control in these patients. Methods We enrolled 31 patients with T2DM on HD. They were divided into two groups according to duration of HD: ≤6 months (short HD group, N = 16) and >6 months (long HD group, N = 15). GA or adjusted GA and parameters of glycemic control obtained by continuous glucose monitoring were measured, and the correlations between these were analyzed. Results GA and adjusted GA were significantly correlated with mean glucose levels (r = 0.400, P = 0.025 and r = 0.508, P = 0.0037) in all patients. Similar results were obtained in the long HD group (GA: r = 0.554, P = 0.032; adjusted GA: r = 0.604, P = 0.017). However, in the short HD group, adjusted GA (r = 0.502, P = 0.047) but not GA (r = 0.340, P = 0.20) was significantly correlated with mean glucose levels. Conclusions Adjusted GA may be a better indicator than GA for evaluating glycemic control in T2DM patients with short duration of HD.

本文言語English
ページ(範囲)148-153
ページ数6
ジャーナルDiabetes Research and Clinical Practice
130
DOI
出版ステータスPublished - 08-2017

All Science Journal Classification (ASJC) codes

  • 内科学
  • 内分泌学、糖尿病および代謝内科学
  • 内分泌学

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