Serum collagenase-like peptidase activity in rheumatoid arthritis and systemic lupus erythematosus

Iwase Okadaa Kimi; Nagatsua Toshiharu; Fujita Keisuke; Torikai Katsutaka; Hamamoto Tatsuo; Shibata Tsunehiro; Maeno Yoshimasa; Sakakibara Shumpei

doi:10.1016/0009-8981(85)90125-1

Serum collagenase-like peptidase activity in rheumatoid arthritis and systemic lupus erythematosus

Iwase Okadaa Kimi
, Nagatsua Toshiharu
, Fujita Keisuke
, Torikai Katsutaka
, Hamamoto Tatsuo
, Shibata Tsunehiro
, Maeno Yoshimasa
, Sakakibara Shumpei

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

4 被引用数 (Scopus)

抄録

Collagenase-like(CL) peptidase activity in serum, which was measured using a newly synthesized substrate, (succinyl-Gly-Pro-Leu-Gly-Pro)-4-methylcoumaryl-7-amide, was significantly lower in patients with advanced rheumatoid arthritis or with systemic lupus erythematosus than that in normal controls. Decrease of the serum enzyme activity was more pronounced in systemic lupus erythematosus. No significant change in serum CL-peptidase activity was found in other connective tissue diseases such as mixed connective tissue disease and Sjogren's syndrome.

本文言語	英語
ページ（範囲）	75-79
ページ数	5
ジャーナル	Clinica Chimica Acta
巻	146
号	1
DOI	https://doi.org/10.1016/0009-8981(85)90125-1
出版ステータス	出版済み - 28-02-1985
外部発表	はい

All Science Journal Classification (ASJC) codes

生化学
臨床生化学
生化学、医学

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10.1016/0009-8981(85)90125-1

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title = "Serum collagenase-like peptidase activity in rheumatoid arthritis and systemic lupus erythematosus",

abstract = "Collagenase-like(CL) peptidase activity in serum, which was measured using a newly synthesized substrate, (succinyl-Gly-Pro-Leu-Gly-Pro)-4-methylcoumaryl-7-amide, was significantly lower in patients with advanced rheumatoid arthritis or with systemic lupus erythematosus than that in normal controls. Decrease of the serum enzyme activity was more pronounced in systemic lupus erythematosus. No significant change in serum CL-peptidase activity was found in other connective tissue diseases such as mixed connective tissue disease and Sjogren's syndrome.",

keywords = "Collagenase - like peptidase, Serum rheumatoid arthritis, Systemic lupus erythematosus",

author = "Kimi, \{Iwase Okadaa\} and Nagatsua Toshiharu and Fujita Keisuke and Torikai Katsutaka and Hamamoto Tatsuo and Shibata Tsunehiro and Maeno Yoshimasa and Sakakibara Shumpei",

year = "1985",

month = feb,

day = "28",

doi = "10.1016/0009-8981(85)90125-1",

language = "English",

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TY - JOUR

T1 - Serum collagenase-like peptidase activity in rheumatoid arthritis and systemic lupus erythematosus

AU - Kimi, Iwase Okadaa

AU - Toshiharu, Nagatsua

AU - Keisuke, Fujita

AU - Katsutaka, Torikai

AU - Tatsuo, Hamamoto

AU - Tsunehiro, Shibata

AU - Yoshimasa, Maeno

AU - Shumpei, Sakakibara

PY - 1985/2/28

Y1 - 1985/2/28

N2 - Collagenase-like(CL) peptidase activity in serum, which was measured using a newly synthesized substrate, (succinyl-Gly-Pro-Leu-Gly-Pro)-4-methylcoumaryl-7-amide, was significantly lower in patients with advanced rheumatoid arthritis or with systemic lupus erythematosus than that in normal controls. Decrease of the serum enzyme activity was more pronounced in systemic lupus erythematosus. No significant change in serum CL-peptidase activity was found in other connective tissue diseases such as mixed connective tissue disease and Sjogren's syndrome.

AB - Collagenase-like(CL) peptidase activity in serum, which was measured using a newly synthesized substrate, (succinyl-Gly-Pro-Leu-Gly-Pro)-4-methylcoumaryl-7-amide, was significantly lower in patients with advanced rheumatoid arthritis or with systemic lupus erythematosus than that in normal controls. Decrease of the serum enzyme activity was more pronounced in systemic lupus erythematosus. No significant change in serum CL-peptidase activity was found in other connective tissue diseases such as mixed connective tissue disease and Sjogren's syndrome.

KW - Collagenase - like peptidase

KW - Serum rheumatoid arthritis

KW - Systemic lupus erythematosus

UR - https://www.scopus.com/pages/publications/0021880773

UR - https://www.scopus.com/pages/publications/0021880773#tab=citedBy

U2 - 10.1016/0009-8981(85)90125-1

DO - 10.1016/0009-8981(85)90125-1

M3 - Article

C2 - 2985298

AN - SCOPUS:0021880773

SN - 0009-8981

VL - 146

SP - 75

EP - 79

JO - Clinica Chimica Acta

JF - Clinica Chimica Acta

IS - 1

ER -

Serum collagenase-like peptidase activity in rheumatoid arthritis and systemic lupus erythematosus

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