TY - JOUR
T1 - Serum concentrations of carotenoids, retinol, and α-tocopherol in healthy persons determined by high-performance liquid chromatography
AU - Ito, Yoshinori
AU - Ochiai, Junichi
AU - Sasaki, Ryuichiro
AU - Suzuki, Sadao
AU - Kusuhara, Yasuhiro
AU - Morimitsu, Youichi
AU - Otani, Motohiko
AU - Aoki, Kunio
N1 - Funding Information:
We are deeply indebted to Mr. Y. Kobayashi and Miss M. Shinohara for technical assistance and to Prof. S. Ito (Fujita Health University) and Dr. T. Maoka (Kyoto College of Pharmacy) for valuable discussion. We thank Dr. K. Sueki (Japan Roche Co., Ltd.) for the gift of P-cryptoxanthin, canthaxanthin, and zeaxanthin. This work was supported in part by a Grant-in-Aid from the Ministry of Education, Science and Culture for the Committee of Project Policy for Overseas Cancer Research (No. 63042004).
PY - 1990/12/24
Y1 - 1990/12/24
N2 - Serum concentrations of α-carotene (AC), β-carotene (BC), lycopene (LY), β-cryptoxanthin (CR), zeaxanthin (including lutein, ZX), canthaxanthin (CX), retinol (RE), and α-tocopherol (TO) in healthy persons (618 males and 1196 females) aged 7-86 years were determined by HPLC. Serum concentrations of BC among persons aged 20-49 years were higher with increasing age in females, but not in males. Serum CR concentrations decreased with age ranging from 7 to 39 years, while ZX concentrations rose in the age group of 20 to 59 years for both sexes. In contrast, serum RE concentrations and ratios of RE BC and RE CR, especially in males aged 20-49, were higher with age. Serum TO values in both sexes rose with age and were similar.
AB - Serum concentrations of α-carotene (AC), β-carotene (BC), lycopene (LY), β-cryptoxanthin (CR), zeaxanthin (including lutein, ZX), canthaxanthin (CX), retinol (RE), and α-tocopherol (TO) in healthy persons (618 males and 1196 females) aged 7-86 years were determined by HPLC. Serum concentrations of BC among persons aged 20-49 years were higher with increasing age in females, but not in males. Serum CR concentrations decreased with age ranging from 7 to 39 years, while ZX concentrations rose in the age group of 20 to 59 years for both sexes. In contrast, serum RE concentrations and ratios of RE BC and RE CR, especially in males aged 20-49, were higher with age. Serum TO values in both sexes rose with age and were similar.
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U2 - 10.1016/0009-8981(90)90128-F
DO - 10.1016/0009-8981(90)90128-F
M3 - Article
C2 - 2128764
AN - SCOPUS:0025652055
SN - 0009-8981
VL - 194
SP - 131
EP - 144
JO - Clinica Chimica Acta
JF - Clinica Chimica Acta
IS - 2-3
ER -