Simple disk-based method for detection of Klebsiella pneumoniae carbapenemase-type β-lactamase by use of a boronic acid compound

Yohei Doi; Brian A. Potoski; Jennifer M. Adams-Haduch; Hanna E. Sidjabat; Anthony W. Pasculle; David L. Paterson

doi:10.1128/JCM.01408-08

Simple disk-based method for detection of Klebsiella pneumoniae carbapenemase-type β-lactamase by use of a boronic acid compound

Yohei Doi
, Brian A. Potoski
, Jennifer M. Adams-Haduch
, Hanna E. Sidjabat
, Anthony W. Pasculle
, David L. Paterson

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

146 被引用数 (Scopus)

抄録

A disk potentiation method using carbapenems as substrates and 3-aminophenyl boronic acid as an inhibitor was evaluated for the detection of Klebsiella pneumoniae carbapenemase (KPC)-type β-lactamases. When combined with nonsusceptibility to ertapenem, the method was easy to perform and reliably differentiated isolates producing KPC-type β-lactamases from those producing other types of β-lactamases.

本文言語	英語
ページ（範囲）	4083-4086
ページ数	4
ジャーナル	Journal of clinical microbiology
巻	46
号	12
DOI	https://doi.org/10.1128/JCM.01408-08
出版ステータス	出版済み - 12-2008
外部発表	はい

All Science Journal Classification (ASJC) codes

微生物学（医療）

文献へのアクセス

10.1128/JCM.01408-08

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引用スタイル

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abstract = "A disk potentiation method using carbapenems as substrates and 3-aminophenyl boronic acid as an inhibitor was evaluated for the detection of Klebsiella pneumoniae carbapenemase (KPC)-type β-lactamases. When combined with nonsusceptibility to ertapenem, the method was easy to perform and reliably differentiated isolates producing KPC-type β-lactamases from those producing other types of β-lactamases.",

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