Squamous cell carcinoma arising within oral florid papillomatosis; A report of two cases

Makoto Urano, Shigenobu Iwata, Kensei Naito, Kazuo Sakurai, Shigeki Mori, Yoshihiro Iwata, Katsuhiko Komori, Makoto Kuroda

研究成果: Article査読

抄録

We treated two patients with oral florid papillomatosis (OFF) of the buccal mucosa, which developed into squamous cell carcinoma during a long term follow-up period. The first is a 62-year-old female who developed to squamous cell carcinoma 13 years after OFF, and the second is a 65-year-old female who developed it after 9 years. Both were resistant to laser surgery, irradiation, and chemotherapy, and had agressive local infiltration. In the second case, autopsy revealed generalized métastases. The clinical and pathological characteristics of OFF were tendency of frequent local recurrence, resistance to treatment, and broad papillary proliferation in the basal layer of the epithelium. A review of the literature and a discussion of the histopathological features and treatment of OFF are also presented in this paper.

本文言語English
ページ(範囲)955-961
ページ数7
ジャーナルPractica Otologica
89
8
DOI
出版ステータスPublished - 1996

All Science Journal Classification (ASJC) codes

  • Otorhinolaryngology

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