Study of Skin Safety of S-3440 Sol

Kayoko Matsunaga, Kumiko Ohiwa, Chikako Ukei, Ritsuko Hayakawa

研究成果: Article査読

抄録

In order to evaluate the skin safety of 0. 064% betamethasone 17, 21-dipropionate (S-3440) sol product and the product�s vehicle offered by Shionogi and Co., Ltd., a 48 hours occlusive patch test was performed using thirty three patients with dermatoses related to topical medicaments. The results showed that no patient had allergic reactions to either the product or its vehicle. Their skin irritancy indices were 4. 5 and 1.5, respectively, and their skin reaction patterns were evaluated as type I, which is regarded as the least irritating topical agents. Besides S-3440 Sol product, the skin safety of Rinderon-DP Cream and Ointment, Rinderon-V Cream and Ointment, and Rinderon-VG Cream, Ointment and Lotion were also evaluated. All of the products showed skin irritancy indices of less than or equal to 4. 5 and type I skin reaction patterns. Therefore, it was concluded that these products are excellent from the standpoint of skin safety.

本文言語English
ページ(範囲)259-263
ページ数5
ジャーナルskin research
26
2
DOI
出版ステータスPublished - 01-01-1984
外部発表はい

All Science Journal Classification (ASJC) codes

  • 皮膚病学
  • 感染症

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