Surgical outcomes and quality of life assessment of esophagectomy for cancer with colon conduit via retrosternal route

Vo Duy Long, Dang Quang Thong, Nguyen Viet Hai, Tran Quang Dat, Ho Le Minh Quoc, Doan Thuy Nguyen, Nguyen Vu Tuan Anh, Tran Anh Minh, Nguyen Lam Vuong, Jimmy Bok Yan So, Nguyen Hoang Bac, Ichiro Uyama

研究成果: ジャーナルへの寄稿学術論文査読

2 被引用数 (Scopus)


Purpose: Colon conduit is an alternative to a gastric conduit for esophagectomy in patients that stomach is not available. Surgical technique is complex and has a high risk of morbidities and mortality. Outcomes of patients are still lacking in the literature, thus aims of this study are to evaluate the safety, feasibility and long-term functional outcomes of patients who underwent esophagectomy for cancer with colon conduit via retrosternal route. Methods: Twenty-six patients underwent operation between August 2016 and June 2021 for malignancies. Minimally invasive esophagectomy and laparotomy were performed in accordance with the 2017 Japan Esophageal Society’s guidelines. Colonic interposition was used for esophageal replacement. Outcomes were technical success, complications assessed using Clavien-Dindo classification, and patient’s quality of life (QOL) based on EORTC-QOL-OES18 questionnaire. Results: Mean age was 56.0 ± 9.9 years and 21 patients (80.8%) were men. Mean operating time was 432 ± 66 min. Technical success was 100%. The average number of resected lymph nodes was 26 ± 14. Twelve patients (46.2%) experienced postoperative complications: 7/12 were classified as grade I-II, 3/12 as grade III, 1/12 as grade IV, and 1/12 as grade V (death). Patient’s QOL improved during the follow-up period with median (25–75th percentiles) global EORTC-QOL-OES18 score was 29 (17–34); 13 (9–21), and 9 (6–16) at 3, 6, and 12 months, respectively. During the follow-up period, there were 4 late complications, 3 lymphatic recurrences, 5 distant metastases, and 6 deaths. Conclusions: Colon conduit via retrosternal route after esophagectomy is feasible, safe, and could provide acceptable long-term functional outcomes.

出版ステータス出版済み - 07-2023

All Science Journal Classification (ASJC) codes

  • 消化器病学


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