TY - JOUR
T1 - Swine as an allotransplantation model
AU - Kenmochi, Takashi
AU - Mullen, Yoko
AU - Miyamoto, Masaaki
AU - Stein, Elizabeth
PY - 1994/10
Y1 - 1994/10
N2 - Because of their anatomical and physiological similarities to humans, pigs are well suited for solving technical problems associated with clinical transplantation. The availability of genetically defined strains of miniature swine is unique with this species, and has permitted the investigation, in a large animal model, of immunological and genetic aspects of allograft rejection, clinical manifestations associated with bone marrow transplantation, and the feasibility of various approaches for induction of transplantation tolerance. Immunological assays and various reagents are also available in order to pursue these studies.
AB - Because of their anatomical and physiological similarities to humans, pigs are well suited for solving technical problems associated with clinical transplantation. The availability of genetically defined strains of miniature swine is unique with this species, and has permitted the investigation, in a large animal model, of immunological and genetic aspects of allograft rejection, clinical manifestations associated with bone marrow transplantation, and the feasibility of various approaches for induction of transplantation tolerance. Immunological assays and various reagents are also available in order to pursue these studies.
UR - https://www.scopus.com/pages/publications/0027943950
UR - https://www.scopus.com/pages/publications/0027943950#tab=citedBy
U2 - 10.1016/0165-2427(94)90134-1
DO - 10.1016/0165-2427(94)90134-1
M3 - Article
C2 - 7856050
AN - SCOPUS:0027943950
SN - 0165-2427
VL - 43
SP - 177
EP - 183
JO - Veterinary Immunology and Immunopathology
JF - Veterinary Immunology and Immunopathology
IS - 1-3
ER -