Task dependency of the long-latency facilitatory effect on the soleus H-reflex by cerebellar transcranial magnetic stimulation

Akiyoshi Matsugi, Nobuhiko Mori, Shintaro Uehara, Noriyuki Kamata, Kosuke Oku, Kouichi Mukai, Kiyoshi Nagano

研究成果: Article査読

13 被引用数 (Scopus)

抄録

We investigated whether cerebellar transcranial magnetic stimulation (C-TMS) facilitates the excitability of the ipsilateral soleus motoneuron pool in resting humans, and whether the facilitation is modulated by a task that promotes cerebellar activity. A test tibial nerve stimulus evoking the H-reflex from the right soleus muscle was delivered before or after conditioning C-TMS in prone individuals. The amplitude of the H-reflex was significantly increased at conditioning-test interstimulus intervals of 110, 120, and 130 ms. Furthermore, we revealed that this facilitation effect was inhibited while the individuals tapped their right index finger. These findings indicate that C-TMS facilitates spinal motoneuronal excitability with an ∼100ms latency in resting humans, and that this cerebellar spinal facilitation is modulated by a task that might increase cerebellar activity. Cerebellar spinal facilitation could thus be useful for assessing the excitability of the cerebellum, or the cerebellar output to spinal motoneurons.

本文言語English
ページ(範囲)1375-1380
ページ数6
ジャーナルNeuroreport
25
17
DOI
出版ステータスPublished - 03-12-2014
外部発表はい

All Science Journal Classification (ASJC) codes

  • 神経科学(全般)

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