The comparison of the prognosis between Epstein-Barr virus (EBV)-positive gastric carcinomas and EBV-negative ones

Yuko Kijima, Sumiya Ishigami, Shuichi Hokita, Chihaya Koriyama, Suminori Akiba, Yoshito Eizuru, Takashi Aikou

研究成果: Article査読

49 被引用数 (Scopus)

抄録

The relationship between the degree of lymphocytic infiltration into the tumor and the prognosis has not been completely evaluated between Epstein-Barr virus (EBV)-positive and -negative gastric carcinoma (GC). Although the average numbers and the grades of the infiltrating CD8+T cells, natural killer cells, dendritic cells, Ki67-positive cells were significantly greater in EBV-positive GCs than in -negative GCs, there was no significant survival improvement in EBV-positive group. These findings suggest that the infiltration of lymphocytes in the EBV-positive GC does not necessarily meant better prognosis and that the EBV status is not a significant prognostic factor in the patients with gastric cancer.

本文言語English
ページ(範囲)33-40
ページ数8
ジャーナルCancer Letters
200
1
DOI
出版ステータスPublished - 08-10-2003
外部発表はい

All Science Journal Classification (ASJC) codes

  • 腫瘍学
  • 癌研究

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