The human homolog of Sex comb on midleg (SCMH1) maps to chromosome 1p34

Joel Berger, Hiroki Kurahashi, Yoshihiro Takihara, Kazunori Shimada, Hugh W. Brock, Filippo Randazzo

研究成果: Article

20 引用 (Scopus)

抜粋

Polycomb group genes were originally identified in Drosophila as repressors required to maintain the silenced state of homeotic loci. About ten Polycomb group genes have been cloned in Drosophila, and mammalian homologs have been identified for most of these. Here, we isolate cDNAs encoding two isoforms of a human homolog of Drosophila Sex comb on midleg (Scm), named Sex comb on midleg homolog-1 (SCMH1). Overall, SCMH1 has 94% identity to its mouse counterpart Scmh1, and 41% identity to Scm, and contains two l (3)mbt domains, and the SPM domain that are characteristic of Scm. SCMH1 is widely expressed in adult tissues, and maps to chromosome 1p34. (C) 1999 Elsevier Science B.V. All rights reserved.

元の言語English
ページ(範囲)185-191
ページ数7
ジャーナルGene
237
発行部数1
DOI
出版物ステータスPublished - 03-09-1999
外部発表Yes

All Science Journal Classification (ASJC) codes

  • Genetics

フィンガープリント The human homolog of Sex comb on midleg (SCMH1) maps to chromosome 1p34' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

  • これを引用

    Berger, J., Kurahashi, H., Takihara, Y., Shimada, K., Brock, H. W., & Randazzo, F. (1999). The human homolog of Sex comb on midleg (SCMH1) maps to chromosome 1p34. Gene, 237(1), 185-191. https://doi.org/10.1016/S0378-1119(99)00285-1