The outer membrane fraction of Flavobacterium psychrophilum induces protective immunity in rainbow trout and ayu

M. Habibur Rahman, Akashi Kuroda, Johannes M. Dijkstra, Ikunari Kiryu, Teruyuki Nakanishi, Mitsuru Ototake

研究成果: Article査読

64 被引用数 (Scopus)

抄録

Flavobacterium psychrophilum is the causative agent of coldwater disease, which is responsible for serious losses in fish aquaculture in several parts of the world. No commercial vaccines are currently available for the prevention of coldwater disease. The present study sought to assess the efficacy of a F. psychrophilum vaccine based on the antigenic outer membrane fraction (OMF). This fraction induced significantly higher protection against coldwater disease in both rainbow trout (Oncorhynchus mykiss) and ayu (Plecoglossus altivelis) compared to inactivated whole cell F. psychrophilum bacterin. Coincident with higher protection, sera of fish immunised with the OMF vaccine had higher agglutination titres than those of fish immunised with inactivated whole cell F. psychrophilum.

本文言語English
ページ(範囲)169-179
ページ数11
ジャーナルFish and Shellfish Immunology
12
2
DOI
出版ステータスPublished - 2002
外部発表はい

All Science Journal Classification (ASJC) codes

  • Environmental Chemistry
  • Aquatic Science

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