Therapeutic Effect of Lisuride Maleate on Post-stroke Depression

Hidetaka Hougaku, Masayasu Matsumoto, Ryuji Hata, Nobuo Handa, Masatoshi Imaizumi, Yoshinori Sugitani, Shotaro Yoneda, Hideki Etani, Kenji Sueyoshi, Masahito Kusunoki, Takenobu Kamada, Osamu Uyama

研究成果: Article

7 引用 (Scopus)

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Twenty post-stroke depressive patients who obtained more than 11 points on Self-Rating Questionnaire for Depression, were treated with 0.075 mg/day lisuride maleate for 12 weeks. The drug effect on depression was evaluated quantitatively by the Hamilton Rating Scale for Depression. The relationships between brain CT or MRI and SRQ-D score were investigated in 24 subjects. More than 80% of post-stroke depressive patients improved after lisuride maleate treatment for 8 or 12 weeks. In particular, depressed mood, hypobulia, sleep disturbance, anxiety, etc. were significantly improved compared to the baseline condition. As for the relationships with CT and/or MRI findings, the group with moderate to severe brain atrophy had a significantly higher grade of depressive state than those without.

元の言語English
ページ(範囲)52-59
ページ数8
ジャーナルNippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics
31
発行部数1
DOI
出版物ステータスPublished - 01-01-1994
外部発表Yes

All Science Journal Classification (ASJC) codes

  • Geriatrics and Gerontology

フィンガープリント Therapeutic Effect of Lisuride Maleate on Post-stroke Depression' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

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    Hougaku, H., Matsumoto, M., Hata, R., Handa, N., Imaizumi, M., Sugitani, Y., Yoneda, S., Etani, H., Sueyoshi, K., Kusunoki, M., Kamada, T., & Uyama, O. (1994). Therapeutic Effect of Lisuride Maleate on Post-stroke Depression. Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics, 31(1), 52-59. https://doi.org/10.3143/geriatrics.31.52