Three cases of Kimura's disease

K. Yoneda, T. Nakajima, Y. Yoshimura, M. Kobayashi, T. Nishiyama

研究成果: Article査読


The characteristic clinical sign leading to a diagnosis of Kimura's disease (eosinophilic granulomatosis of the soft tissue) is the presence of a subcutaneous mass, usually in the region of the head and neck, which can be confirmed on a histological examination of this tissue. Although many ways of treating this disease have been reported, a definitive method has not yet been established. A surgical excision or radiation and steroid therapy have been the primary ways. However, any one of these methods used independently has led to a high incidence of recurrence. In this report, the authors discuss three cases of Kimura's disease and describe their method of treatment, using a form of combined therapy. Surgery is performed to reduce the size of the tumor mass, and depending on the amount of the peripheral eosinophiles, additional steroid and/or radiation treatment is also carried out. Of cases so treated, the longest observation period after surgery has been 5 years, and there have been no instances of a recurrence of the tumor. As a result of our experience, we feel that a combined therapy is useful for treating Kumura's disease, and that additional therapy is heeded to suppress eosinophilic production so as to prevent tumor regrowth.

ジャーナルJapanese Journal of Plastic and Reconstructive Surgery
出版ステータスPublished - 1989

All Science Journal Classification (ASJC) codes

  • 外科


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